biostudies-literatureSmit AKNational Health and Medical Research CouncilUniversity of Sydney1581https://www.ebi.ac.uk/biostudies/studies/S-EPMC9605561biostudies-literatureUnknown12(10)Personalized polygenic risk information may be used to guide risk-based melanoma prevention and early detection at a population scale, but research on communicating this information is limited. This mixed-methods study aimed to assess the acceptability of a genetic counselor (GC) phone call in communicating polygenic risk information in the Melanoma Genomics Managing Your Risk randomized controlled trial. Participants (<i>n</i> = 509) received personalized melanoma polygenic risk information, an educational booklet on melanoma prevention, and a GC phone call, which was audio-recorded. Participants completed the Genetic Counseling Satisfaction Survey 1-month after receiving their risk information (<i>n</i> = 346). A subgroup took part in a qualitative interview post-study completion (<i>n</Journal of personalized medicineCommunicating Personal Melanoma Polygenic Risk Information: Participants' Experiences of Genetic Counseling in a Community-Based Study.PMC9605561AKS received a Research Training Program (RTP) Stipend Scholarship and a Merit Top Up Scholarship from the University of Sydney, and a Melanoma Institute Australia Postgraduate Research Scholarshipproject grant (1129822)AEC was funded by fellowships from the NHMRC (1147843 and 2008454)Turbitt EMcGovern MCust AEEspinoza DSmit AKOn Behalf Of The Managing Your Risk Study GroupKirk JFenton GLInnes JSLimb SfalseCommunicating Personal Melanoma Polygenic Risk Information: Participants' Experiences of Genetic Counseling in a Community-Based Study.Personalized polygenic risk information may be used to guide risk-based melanoma prevention and early detection at a population scale, but research on communicating this information is limited. This mixed-methods study aimed to assess the acceptability of a genetic counselor (GC) phone call in communicating polygenic risk information in the Melanoma Genomics Managing Your Risk randomized controlled trial. Participants (<i>n</i> = 509) received personalized melanoma polygenic risk information, an educational booklet on melanoma prevention, and a GC phone call, which was audio-recorded. Participants completed the Genetic Counseling Satisfaction Survey 1-month after receiving their risk information (<i>n</i> = 346). A subgroup took part in a qualitative interview post-study completion (<i>n</2022-01-01T00:00:00Z2022 Sep2025-04-18T21:20:54.303Z2025-04-07T09:14:42.185ZS-EPMC96055613629472010.3390/jpm12101581