{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wu Q"],"funding":["Innovation and entrepreneurship training program for college students of Jiangxi 474 University of traditional Chinese medicine","Jiangxi University of Traditional Chinese Medicine 472 first-class discipline construction research start-up fund"],"pagination":["6893"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9611113"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(20)"],"pubmed_abstract":["Alzheimer's disease is the most common neurodegenerative disease, characterized by memory loss and cognitive dysfunction. Raspberry fruits contain polyphenols which have antioxidant and anti-inflammatory properties. In this study, we used molecular imprinting technology to efficiently isolate phenolic components from the raspberry ethyl acetate extracts. Six phenolic components (ellagic acid, tiliroside, kaempferol-3-o-rutoside, gallic acid, ferulic acid and vanillic acid) were identified by UPLC-Q-TOF-MS analysis. Molecular docking was used to predict the anti-inflammatory effects and anti-Alzheimer's potential of these isolated compounds, which showed a good binding ability to diseases and related proteins. However, the binding energy and docking fraction of ellagic acid, tiliroside, and"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Isolation of Phenolic Compounds from Raspberry Based on Molecular Imprinting Techniques and Investigation of Their Anti-Alzheimer's Disease Properties."],"pmcid":["PMC9611113"],"funding_grant_id":["S20211042013","0071"],"pubmed_authors":["Naeem A","Zou J","Yu C","Chen J","Ping Y","Wu Q","Wang Y"],"additional_accession":[]},"is_claimable":false,"name":"Isolation of Phenolic Compounds from Raspberry Based on Molecular Imprinting Techniques and Investigation of Their Anti-Alzheimer's Disease Properties.","description":"Alzheimer's disease is the most common neurodegenerative disease, characterized by memory loss and cognitive dysfunction. Raspberry fruits contain polyphenols which have antioxidant and anti-inflammatory properties. In this study, we used molecular imprinting technology to efficiently isolate phenolic components from the raspberry ethyl acetate extracts. Six phenolic components (ellagic acid, tiliroside, kaempferol-3-o-rutoside, gallic acid, ferulic acid and vanillic acid) were identified by UPLC-Q-TOF-MS analysis. Molecular docking was used to predict the anti-inflammatory effects and anti-Alzheimer's potential of these isolated compounds, which showed a good binding ability to diseases and related proteins. However, the binding energy and docking fraction of ellagic acid, tiliroside, and","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-05-29T14:37:21.246Z","creation":"2024-10-19T01:43:03.31Z"},"accession":"S-EPMC9611113","cross_references":{"pubmed":["36296486"],"doi":["10.3390/molecules27206893"]}}