{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["62(5)"],"submitter":["Bobylev D"],"funding":["European Union's Seventh Framework Programme for Research","European Union’s Seventh Framework Programme for Research"],"pubmed_abstract":["<h4>Objectives</h4>Early results from the prospective ESPOIR Trial have indicated excellent results for pulmonary valve replacement using decellularized pulmonary homografts (DPH).<h4>Methods</h4>A 5-year analysis of ESPOIR Trial patients was performed to provide an insight into the midterm DPH performance. ESPOIR Trial and Registry patients were matched with cryopreserved homografts (CH) patients considering patient age, type of heart defect and previous procedures to present the overall experience with DPH.<h4>Results</h4>A total of 121 patients (59 female) were prospectively enrolled (8/2014-12/2016), median age 16.5 years (interquartile range 11.2-29.8), and median DPH diameter 24 mm. One death (73 year-old) occurred during a median follow-up of 5.9 years (5.4-6.4), in addition to 2 pe"],"journal":["European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery"],"pagination":["ezac219"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9615428"],"repository":["biostudies-literature"],"pubmed_title":["5-Year results from the prospective European multi-centre study on decellularized homografts for pulmonary valve replacement ESPOIR Trial and ESPOIR Registry data."],"pmcid":["PMC9615428"],"pubmed_authors":["Tsang V","Dave H","Padalino M","Horke A","Tudorache I","Ciubotaru A","Andreeva A","Cheptanaru E","Hazekamp M","Vida V","Haverich A","Laufer G","Schmiady M","Jashari R","Sarikouch S","Boethig D","Bobylev D","Cebotari S","Meyns B","Rega F","Andreas M"],"additional_accession":[]},"is_claimable":false,"name":"5-Year results from the prospective European multi-centre study on decellularized homografts for pulmonary valve replacement ESPOIR Trial and ESPOIR Registry data.","description":"<h4>Objectives</h4>Early results from the prospective ESPOIR Trial have indicated excellent results for pulmonary valve replacement using decellularized pulmonary homografts (DPH).<h4>Methods</h4>A 5-year analysis of ESPOIR Trial patients was performed to provide an insight into the midterm DPH performance. ESPOIR Trial and Registry patients were matched with cryopreserved homografts (CH) patients considering patient age, type of heart defect and previous procedures to present the overall experience with DPH.<h4>Results</h4>A total of 121 patients (59 female) were prospectively enrolled (8/2014-12/2016), median age 16.5 years (interquartile range 11.2-29.8), and median DPH diameter 24 mm. One death (73 year-old) occurred during a median follow-up of 5.9 years (5.4-6.4), in addition to 2 pe","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-06-01T00:33:09.641Z","creation":"2025-06-01T00:33:09.641Z"},"accession":"S-EPMC9615428","cross_references":{"pubmed":["35425983"],"doi":["10.1093/ejcts/ezac219"]}}