{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang W"],"funding":["Foundation of Shanghai Municipal Health Commission","Foundation of Chongming","Clinical Research Plan of Shanghai Tenth People’s Hospital","Fundamental Research Funds for Central Universities","Chinese National Natural Science Foundation","Clinical Research Plan of SHDC","Shanghai Natural Science Foundation of China"],"pagination":["222"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9618191"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21(1)"],"pubmed_abstract":["Background
Coronary microvascular dysfunction (CMD) is common and is associated with unfavorable cardiovascular events in patients with diabetes mellitus (DM). Coronary angiography-derived index of microcirculatory resistance (caIMR) is a recently developed wire- and hyperemic agent-free method to assess CMD. We aimed to investigate the prognostic impact of CMD assessed by caIMR on clinical outcomes in patients with DM and chronic coronary syndrome (CCS).Methods
CCS patients who underwent coronary angiography between June 2015 to May 2018 were included. Coronary microvascular function was measured by caIMR, and CMD was defined as caIMR ≥ 25U. The primary endpoint was major adverse cardiac events (MACE). Kaplan-Meier analysis and Cox proportional hazards models were used to "],"journal":["Cardiovascular diabetology"],"pubmed_title":["Prognostic value of coronary microvascular dysfunction assessed by coronary angiography-derived index of microcirculatory resistance in diabetic patients with chronic coronary syndrome."],"pmcid":["PMC9618191"],"funding_grant_id":["22120190211","82170521","CKY2021-21, CKY2020-29","202140263","SHDC2020CR4065","YNCR2A001","21ZR1449500"],"pubmed_authors":["Mareai RM","Mohammed AA","Liu L","Lv X","Jiang R","Shi T","Feng C","Abdu FA","Zhang W","Yin G","Mohammed AQ","Che W","Xu S","Singh S","Yu X","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"Prognostic value of coronary microvascular dysfunction assessed by coronary angiography-derived index of microcirculatory resistance in diabetic patients with chronic coronary syndrome.","description":"Background
Coronary microvascular dysfunction (CMD) is common and is associated with unfavorable cardiovascular events in patients with diabetes mellitus (DM). Coronary angiography-derived index of microcirculatory resistance (caIMR) is a recently developed wire- and hyperemic agent-free method to assess CMD. We aimed to investigate the prognostic impact of CMD assessed by caIMR on clinical outcomes in patients with DM and chronic coronary syndrome (CCS).Methods
CCS patients who underwent coronary angiography between June 2015 to May 2018 were included. Coronary microvascular function was measured by caIMR, and CMD was defined as caIMR ≥ 25U. The primary endpoint was major adverse cardiac events (MACE). Kaplan-Meier analysis and Cox proportional hazards models were used to ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-18T16:56:02.227Z","creation":"2025-04-07T04:22:17.956Z"},"accession":"S-EPMC9618191","cross_references":{"pubmed":["36309724"],"doi":["10.1186/s12933-022-01653-y"]}}