{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Vink E"],"funding":["Liverpool Experimental Cancer Medicine Centre","National Institute for Health Research Health Protection Research Unit","Department for International Development","Medical Research Council","National Institute for Health Research (NIHR)","Bill and Melinda Gates Foundation","EU Platform for","Wellcome Trust","Emerging and Zoonotic Infections at University of Liverpool","Public Health England","European Preparedness Against (Re-)emerging Epidemics"],"pagination":["ofac531"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9619746"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(11)"],"pubmed_abstract":["<h4>Background</h4>We conducted this study to assess the prevalence of viral coinfection in a well characterized cohort of hospitalized coronavirus disease 2019 (COVID-19) patients and to investigate the impact of coinfection on disease severity.<h4>Methods</h4>Multiplex real-time polymerase chain reaction testing for endemic respiratory viruses was performed on upper respiratory tract samples from 1002 patients with COVID-19, aged <1 year to 102 years old, recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK study. Comprehensive demographic, clinical, and outcome data were collected prospectively up to 28 days post discharge.<h4>Results</h4>A coinfecting virus was detected in 20 (2.0%) participants. Multivaria"],"journal":["Open forum infectious diseases"],"pubmed_title":["Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study."],"pmcid":["PMC9619746"],"funding_grant_id":["200927","200907","215091/Z/18/Z","OPP1209135","MC_PC_19059","C18616/A25153","MC_ST_CVR_2019","CO-CIN-01"],"pubmed_authors":["Williams M","Meda M","Sancho-Shimizu V","Thompson AAR","Drummond A","Leiner T","Mortimore K","Patel B","Carlucci N","Maclean A","Little J","Maziere N","Douthwaite S","Rae N","Vincent-Smith L","Bogaert D","Klenerman P","Kaliappan A","Paxton WA","Lillie P","Jain S","Hartley C","Kendall J","Cosgrove C","Mankregod R","Fisher LWS","Finn A","Fletcher T","Shaw VE","Rambaut A","Young P","Caruth V","Post F","Kegg S","Limb J","Waddy S","Papakonstantinou D","Jensen RL","Chechi K","Marsh L","Kiy RT","Docherty AB","Ahmed KA","Summers C","Nagarajan T","Pooni JS","Howard J","Massey H","Turtle LC","Donnelly L","Clarke EA","Bothma P","Wootton DG","Knight SR","Sales D","Spencer RG","Latawiec D","Tatham K","Semple MG","Kasipandian V","Livoti LA","Ridley PM","Pais M","Donegan C","Horby PW","Pintus S","Pius R","Hartshorn S","McCullough K","Vuylsteke A","Tait S","Mclean KA","Ijaz S","Mirfenderesky M","Garcia-Dorival I","Zhang JE","Collini P","Takis P","Thompson C","Drake TM","Roberts S","Laird S","Gunning P","Beadsworth M","Phull M","Pepperell J","Saluja T","Snelson C","Linnett V","Hormis A","Mills G","Armstrong JA","McDonald S","Sharma A","Trochu E","Agwuh K","Zambon M","Davis C","Shaw CA","Liggi S","Sriskandan S","Koch O","Peters M","Evans A","Greenhalf W","Rousseau G","Mok Q","Evans C","Wiselka M","Green CA","Szemiel A","Plotkin D","Nelson M","Gupta RK","Lett L","Lant S","McDonald SE","Koukorava C","Aldera EL","MacNaughton E","Dunn C","Chukkambotla S","Correia GDS","Otahal I","Moon J","Minton J","Pollakis G","Tedder RS","Morris 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D","Stambach T","Solomon T","Dyer P","Ryan B","Dyer T","Dervisevic S","Laha S","Chambler D","Tupper-Carey D","Clark R","Mpenge M","Clark T","Asiimwe IG","Adeniji K","Dalton J","Clohisey S","Barlow SL","Workman A","Jones TR","Whittington A","Scott JT","Lee J","McCafferty S","MacLean A","Whittaker P","Fawkes A","Jacobs M","Thomas J","Vink E","Knight S","Dunning J","MacGillivray L","Shankar-Hari M","Palmieri C","Mohandas K","Hafezi K","Booth L","Best N","Norris L","Saviciute E","Hendry R","Cole S","Tanianis-Hughes J","Mentzer AJ","Dawson C","Fegan C","Takats Z","Berridge J","Goldsmith A","Mitchell J","Merson L","Reynolds T","Price N","Small B","Reynolds W","Stewart R","Shaw V","Shanmuga P","Bullock K","Jones CB","Fullerton D","Cox H","Sands CJ","Cupitt J","Roberts D","Donnison P","Hiscox JA","Maslen L","Roberts M","Burtenshaw A","Allen S","Price D","Burden T","Dumas ME","Law A","Brittain-Long R","Kelsey M","Baillie JK","Szakmany T","Havalda P","Clark JJ","Middleton J","Koshy G","Keating 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M","Alegria A","Whitehouse T","Shah A","Girvan M","Angus B","Smith R","Sigfrid L","Donohue C","ISARIC4C Investigators","Morgan P"],"additional_accession":[]},"is_claimable":false,"name":"Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study.","description":"<h4>Background</h4>We conducted this study to assess the prevalence of viral coinfection in a well characterized cohort of hospitalized coronavirus disease 2019 (COVID-19) patients and to investigate the impact of coinfection on disease severity.<h4>Methods</h4>Multiplex real-time polymerase chain reaction testing for endemic respiratory viruses was performed on upper respiratory tract samples from 1002 patients with COVID-19, aged <1 year to 102 years old, recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK study. Comprehensive demographic, clinical, and outcome data were collected prospectively up to 28 days post discharge.<h4>Results</h4>A coinfecting virus was detected in 20 (2.0%) participants. Multivaria","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-27T02:56:33.102Z","creation":"2024-10-15T07:24:33.303Z"},"accession":"S-EPMC9619746","cross_references":{"pubmed":["36381618"],"doi":["10.1093/ofid/ofac531"]}}