biostudies-literatureUnknown22(6)Andriot TUniversity of GenevaCurrent research indicates deficits in cognitive function together with widespread changes in brain activity following long-term cannabis use. In particular, cannabis use has been associated with excessive spectral power of the alpha rhythm (8-12 Hz), which is also known to be modulated during attentional states. Recent neuroimaging studies have linked heavy cannabis use with structural and metabolic changes in the brain; however, the functional consequences of these changes are still not fully characterized. This study investigated the electrophysiological and behavioral correlates of cannabis dependence by comparing patients with a cannabis use disorder (CUD; N = 24) with cannabis nonuser controls (N = 24), using resting state electroencephalogram (EEG) source-imaging. In addition to evaCognitive, affective & behavioral neuroscience1421-1431https://www.ebi.ac.uk/biostudies/studies/S-EPMC9622528biostudies-literatureElectrophysiological and behavioral correlates of cannabis use disorder.PMC9622528Vuilleumier PAndriot TGinovart NThorens GKhazaal YRos TOhnmacht PfalseElectrophysiological and behavioral correlates of cannabis use disorder.Current research indicates deficits in cognitive function together with widespread changes in brain activity following long-term cannabis use. In particular, cannabis use has been associated with excessive spectral power of the alpha rhythm (8-12 Hz), which is also known to be modulated during attentional states. Recent neuroimaging studies have linked heavy cannabis use with structural and metabolic changes in the brain; however, the functional consequences of these changes are still not fully characterized. This study investigated the electrophysiological and behavioral correlates of cannabis dependence by comparing patients with a cannabis use disorder (CUD; N = 24) with cannabis nonuser controls (N = 24), using resting state electroencephalogram (EEG) source-imaging. In addition to eva2022-01-01T00:00:00Z2022 Dec2025-06-01T00:33:25.97Z2025-06-01T00:33:25.97ZS-EPMC96225283569800410.3758/s13415-022-01016-w