{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Thoms Rodriguez CA"],"pubmed_abstract":["<h4>Introduction</h4>The aim of this study was to investigate the prevalence and distribution of AmpC beta-lactamases (BLs) in uropathogens (<i>E. coli</i> and <i>K. pneumoniae</i>) at the University Hospital of the West Indies Jamaica (UHWI).<h4>Method</h4>De-duplicated consecutive urine samples, collected from January to March 2020 at the UHWI, were analyzed. Screening and phenotypic confirmatory tests were conducted using resistance to cefoxitin and the Disc Approximation Test (DAT) respectively, for isolates of interest. Multiplex PCR was performed on cefoxitin resistant (CR) isolates for the detection of <i>bla</i> <sub>CIT</sub>, <i>bla</i> <sub>MOX</sub>, <i>bla</i> <sub>FOX</sub>, <i>bla</i> <sub>ACC</sub>, and <i>bla</i> <sub>DHA</sub> genes. Whole genome sequencing (WGS) was used"],"journal":["Frontiers in cellular and infection microbiology"],"pagination":["1015633"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9623010"],"repository":["biostudies-literature"],"pubmed_title":["Prevalence and distribution of ampc beta-lactamase producing <i>escherichia coli</i> and <i>klebsiella pneumoniae</i> isolates obtained from urine samples at a tertiary care hospital in the caribbean."],"pmcid":["PMC9623010"],"pubmed_authors":["Cameron J","Seah C","Melano RG","Gossell-Williams M","Reid M","Dawson F","Thoms Rodriguez CA"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence and distribution of ampc beta-lactamase producing <i>escherichia coli</i> and <i>klebsiella pneumoniae</i> isolates obtained from urine samples at a tertiary care hospital in the caribbean.","description":"<h4>Introduction</h4>The aim of this study was to investigate the prevalence and distribution of AmpC beta-lactamases (BLs) in uropathogens (<i>E. coli</i> and <i>K. pneumoniae</i>) at the University Hospital of the West Indies Jamaica (UHWI).<h4>Method</h4>De-duplicated consecutive urine samples, collected from January to March 2020 at the UHWI, were analyzed. Screening and phenotypic confirmatory tests were conducted using resistance to cefoxitin and the Disc Approximation Test (DAT) respectively, for isolates of interest. Multiplex PCR was performed on cefoxitin resistant (CR) isolates for the detection of <i>bla</i> <sub>CIT</sub>, <i>bla</i> <sub>MOX</sub>, <i>bla</i> <sub>FOX</sub>, <i>bla</i> <sub>ACC</sub>, and <i>bla</i> <sub>DHA</sub> genes. Whole genome sequencing (WGS) was used","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-05T14:36:55.035Z","creation":"2024-11-20T08:06:24.512Z"},"accession":"S-EPMC9623010","cross_references":{"pubmed":["36329819"],"doi":["10.3389/fcimb.2022.1015633"]}}