{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Jiang YJ"],"pubmed_abstract":["<h4>Background</h4>The efficacy and safety of neoadjuvant chemotherapy (NAC) in treating resectable synchronous colorectal liver metastases (CRLM) remain controversial.<h4>Methods</h4>Data from CRLM patients who underwent simultaneous liver resection between January 2015 and December 2019 were collected from the Surveillance, Epidemiology, and End Results (SEER) database (SEER cohort, n=305) and a single Chinese Cancer Center (NCC cohort, n=268). Using a 1:2 ratio of propensity score matching (PSM), the prognostic impact of NAC for patients who underwent NAC before surgical treatment and patients who underwent surgical treatment alone was evaluated.<h4>Results</h4>After PSM, there was no significant difference in overall survival (OS) between patients receiving NAC prior to CRLM resection "],"journal":["Frontiers in oncology"],"pagination":["951540"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9623041"],"repository":["biostudies-literature"],"pubmed_title":["Oncological outcomes of neoadjuvant chemotherapy in patients with resectable synchronous colorectal liver metastasis: A result from a propensity score matching study."],"pmcid":["PMC9623041"],"pubmed_authors":["Zhou SC","Chen JH","Liang JW","Jiang YJ"],"additional_accession":[]},"is_claimable":false,"name":"Oncological outcomes of neoadjuvant chemotherapy in patients with resectable synchronous colorectal liver metastasis: A result from a propensity score matching study.","description":"<h4>Background</h4>The efficacy and safety of neoadjuvant chemotherapy (NAC) in treating resectable synchronous colorectal liver metastases (CRLM) remain controversial.<h4>Methods</h4>Data from CRLM patients who underwent simultaneous liver resection between January 2015 and December 2019 were collected from the Surveillance, Epidemiology, and End Results (SEER) database (SEER cohort, n=305) and a single Chinese Cancer Center (NCC cohort, n=268). Using a 1:2 ratio of propensity score matching (PSM), the prognostic impact of NAC for patients who underwent NAC before surgical treatment and patients who underwent surgical treatment alone was evaluated.<h4>Results</h4>After PSM, there was no significant difference in overall survival (OS) between patients receiving NAC prior to CRLM resection ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-19T02:37:55.388Z","creation":"2025-04-07T13:01:58.505Z"},"accession":"S-EPMC9623041","cross_references":{"pubmed":["36330479"],"doi":["10.3389/fonc.2022.951540"]}}