biostudies-literatureAraszczuk AMMinistero dell&apos;Universit? e della RicercaUniversit? degli Studi di Salerno7752-7756https://www.ebi.ac.uk/biostudies/studies/S-EPMC9623583biostudies-literatureUnknown24(42)Head-to-tail cyclization of linear oligoamides containing 4-benzylaminomethyl-1<i>H</i>-1,2,3-triazol-1-yl acetic acid monomers afforded a novel class of "extended macrocyclic peptoids". The identification of the conformation in solution for a cyclodimer and the X-ray crystal structure of a cyclic tetraamide are reported.Organic lettersMacrocyclic Triazolopeptoids: A Promising Class of Extended Cyclic Peptoids.PMC96235832020AEX4TADella Sala GD'Amato AAraszczuk AMPierri GTedesco CSchettini RCostabile CIzzo IDe Riccardis FfalseMacrocyclic Triazolopeptoids: A Promising Class of Extended Cyclic Peptoids.Head-to-tail cyclization of linear oligoamides containing 4-benzylaminomethyl-1<i>H</i>-1,2,3-triazol-1-yl acetic acid monomers afforded a novel class of "extended macrocyclic peptoids". The identification of the conformation in solution for a cyclodimer and the X-ray crystal structure of a cyclic tetraamide are reported.2022-01-01T00:00:00Z2022 Oct2025-04-18T22:51:54.583Z2025-04-07T10:36:07.291ZS-EPMC96235833622307710.1021/acs.orglett.2c03062