biostudies-literatureUnknown19(1)Zhang XM<h4>Background and objective</h4>Patients on parenteral nutrition (PN) are at high risk of both liver and pancreatic injury. More efforts were focused on liver, however, limited data is available to evaluate the effects of PN on pancreas. Thus, we performed a retrospective observational study to evaluate the association between PN and pancreatic injury in Chinese adult patients.<h4>Methods</h4>Adult patients (18-80 years), who received PN for a week or longer, and with repeated measurements of pancreatic enzymes, were included in the analysis. Pancreatic injury was confirmed by serum level of pancreatic amylase (P-AMYwas 53 U/L or higher) or lipase (LP was 63 U/L or higher), which were evaluated at baseline and following every week during PN duration. Age, sex, body weight, height, diagnosNutrition & metabolism73https://www.ebi.ac.uk/biostudies/studies/S-EPMC9624056biostudies-literatureThe association between parenteral nutrition and pancreatic injury in adult patients: a retrospective observational study.PMC9624056Chen ZQXu RSong AQTang MLLi HJZhang XMWan YPZhou YQCai WfalseThe association between parenteral nutrition and pancreatic injury in adult patients: a retrospective observational study.<h4>Background and objective</h4>Patients on parenteral nutrition (PN) are at high risk of both liver and pancreatic injury. More efforts were focused on liver, however, limited data is available to evaluate the effects of PN on pancreas. Thus, we performed a retrospective observational study to evaluate the association between PN and pancreatic injury in Chinese adult patients.<h4>Methods</h4>Adult patients (18-80 years), who received PN for a week or longer, and with repeated measurements of pancreatic enzymes, were included in the analysis. Pancreatic injury was confirmed by serum level of pancreatic amylase (P-AMYwas 53 U/L or higher) or lipase (LP was 63 U/L or higher), which were evaluated at baseline and following every week during PN duration. Age, sex, body weight, height, diagnos2022-01-01T00:00:00Z2022 Oct2025-05-18T13:37:36.134Z2024-10-18T22:07:41.113ZS-EPMC96240563631677410.1186/s12986-022-00706-z