{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5(6)"],"submitter":["Yamaguchi Y"],"pubmed_abstract":["<h4>Introduction</h4><i>SDH</i> Gene mutation is known to be a common cause of pheochromocytoma/paraganglioma and renal cell carcinoma. Here, we report a case of succinate dehydrogenase B-deficient paraganglioma, which has a high risk of metastasis and recurrence, complicated by succinate dehydrogenase-deficient renal cell carcinoma, which is rare and accounts for approximately 0.1% of all renal cell carcinomas.<h4>Case presentation</h4>A 50-year-old man underwent en bloc resection of a retroperitoneal tumor and the right kidney for retroperitoneal paraganglioma and right renal tumor. Both tumors showed negative expressions of succinate dehydrogenase B in immunostaining. The patient was diagnosed with succinate dehydrogenase-deficient paraganglioma and succinate dehydrogenase-deficient ren"],"journal":["IJU case reports"],"pagination":["480-483"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9626355"],"repository":["biostudies-literature"],"pubmed_title":["Succinate dehydrogenase-deficient malignant paraganglioma complicated by succinate dehydrogenase-deficient renal cell carcinoma."],"pmcid":["PMC9626355"],"pubmed_authors":["Tanaka H","Matsuoka Y","Uehara S","Yoshida S","Fujii Y","Nakamura Y","Takemoto A","Fukuda S","Yokoyama M","Yamaguchi Y"],"additional_accession":[]},"is_claimable":false,"name":"Succinate dehydrogenase-deficient malignant paraganglioma complicated by succinate dehydrogenase-deficient renal cell carcinoma.","description":"<h4>Introduction</h4><i>SDH</i> Gene mutation is known to be a common cause of pheochromocytoma/paraganglioma and renal cell carcinoma. Here, we report a case of succinate dehydrogenase B-deficient paraganglioma, which has a high risk of metastasis and recurrence, complicated by succinate dehydrogenase-deficient renal cell carcinoma, which is rare and accounts for approximately 0.1% of all renal cell carcinomas.<h4>Case presentation</h4>A 50-year-old man underwent en bloc resection of a retroperitoneal tumor and the right kidney for retroperitoneal paraganglioma and right renal tumor. Both tumors showed negative expressions of succinate dehydrogenase B in immunostaining. The patient was diagnosed with succinate dehydrogenase-deficient paraganglioma and succinate dehydrogenase-deficient ren","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-27T01:47:36.368Z","creation":"2025-04-06T18:19:44.033Z"},"accession":"S-EPMC9626355","cross_references":{"pubmed":["36341179"],"doi":["10.1002/iju5.12520"]}}