{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Huang M"],"pubmed_abstract":["Qi-Yu-San-Long decoction (QYSLD), a traditional Chinese medicine (TCM) prescription, consisting of ten types of herbal medicine which has significant clinical efficacy in the treatment of non-small cell lung cancer (NSCLC). However, the bioactive ingredients of QYSLD remain unclear, due to their \"multi-ingredients\" and \"multi-targets\" features. This study aimed to construct a spectrum-effect correlation analysis model and screen the potential active components of QYSLD. A fingerprint method based on ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q/TOF-MS) was developed and validated to obtain seventy common peaks of ten batches of QYSLD. The results of methodological evaluation, including precision, repeatability and stability, were less than"],"journal":["Frontiers in pharmacology"],"pagination":["989139"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9627220"],"repository":["biostudies-literature"],"pubmed_title":["Discovering the potential active ingredients of Qi-Yu-San-Long decoction for anti-oxidation, inhibition of non-small cell lung cancer based on the spectrum-effect relationship combined with chemometric methods."],"pmcid":["PMC9627220"],"pubmed_authors":["Li Z","Zhou A","Yang M","Huang M","Li R","Wu H"],"additional_accession":[]},"is_claimable":false,"name":"Discovering the potential active ingredients of Qi-Yu-San-Long decoction for anti-oxidation, inhibition of non-small cell lung cancer based on the spectrum-effect relationship combined with chemometric methods.","description":"Qi-Yu-San-Long decoction (QYSLD), a traditional Chinese medicine (TCM) prescription, consisting of ten types of herbal medicine which has significant clinical efficacy in the treatment of non-small cell lung cancer (NSCLC). However, the bioactive ingredients of QYSLD remain unclear, due to their \"multi-ingredients\" and \"multi-targets\" features. This study aimed to construct a spectrum-effect correlation analysis model and screen the potential active components of QYSLD. A fingerprint method based on ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q/TOF-MS) was developed and validated to obtain seventy common peaks of ten batches of QYSLD. The results of methodological evaluation, including precision, repeatability and stability, were less than","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-03T22:22:54.03Z","creation":"2025-02-19T00:31:52.044Z"},"accession":"S-EPMC9627220","cross_references":{"pubmed":["36339563"],"doi":["10.3389/fphar.2022.989139"]}}