{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Choi HJ"],"funding":["Rural Development Administration","Ministry of Agriculture, Food and Rural Affairs","Korea Smart Farm R&amp;D Foundation","Ministry of Science and ICT, South Korea","National Research Foundation of Korea","Chonnam National University","Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry"],"pagination":["117-125"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9628822"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["32(1)"],"pubmed_abstract":["Until recently, four types of cellobiose-fermenting <i>Saccharomyces cerevisiae</i> strains have been developed by introduction of a cellobiose metabolic pathway based on either intracellular β-glucosidase (GH1-1) or cellobiose phosphorylase (CBP), along with either an energy-consuming active cellodextrin transporter (CDT-1) or a non-energy-consuming passive cellodextrin facilitator (CDT-2). In this study, the ethanol production performance of two cellobiose-fermenting <i>S. cerevisiae</i> strains expressing mutant CDT-2 (N306I) with GH1-1 or CBP were compared with two cellobiose-fermenting <i>S. cerevisiae</i> strains expressing mutant CDT-1 (F213L) with GH1-1 or CBP in the simultaneous saccharification and fermentation (SSF) of cellulose under various conditions. It was found that, regar"],"journal":["Journal of microbiology and biotechnology"],"pubmed_title":["Effects of Engineered <i>Saccharomyces cerevisiae</i> Fermenting Cellobiose through Low-Energy-Consuming Phosphorolytic Pathway in Simultaneous Saccharification and Fermentation."],"pmcid":["PMC9628822"],"funding_grant_id":["421045-03","2020-3893","NRF-2019R1F1A1059516"],"pubmed_authors":["Choi HJ","Jin YS","Lee WH"],"additional_accession":[]},"is_claimable":false,"name":"Effects of Engineered <i>Saccharomyces cerevisiae</i> Fermenting Cellobiose through Low-Energy-Consuming Phosphorolytic Pathway in Simultaneous Saccharification and Fermentation.","description":"Until recently, four types of cellobiose-fermenting <i>Saccharomyces cerevisiae</i> strains have been developed by introduction of a cellobiose metabolic pathway based on either intracellular β-glucosidase (GH1-1) or cellobiose phosphorylase (CBP), along with either an energy-consuming active cellodextrin transporter (CDT-1) or a non-energy-consuming passive cellodextrin facilitator (CDT-2). In this study, the ethanol production performance of two cellobiose-fermenting <i>S. cerevisiae</i> strains expressing mutant CDT-2 (N306I) with GH1-1 or CBP were compared with two cellobiose-fermenting <i>S. cerevisiae</i> strains expressing mutant CDT-1 (F213L) with GH1-1 or CBP in the simultaneous saccharification and fermentation (SSF) of cellulose under various conditions. It was found that, regar","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-04T22:14:57.963Z","creation":"2025-04-04T22:14:57.963Z"},"accession":"S-EPMC9628822","cross_references":{"pubmed":["34949751"],"doi":["10.4014/jmb.2111.11047"]}}