{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Guatelli S"],"funding":["Fundação para a Ciência e a Tecnologia","Università degli Studi di Milano","National Mass Spectrometry Network"],"pagination":["207-227"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9630195"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["390(2)"],"pubmed_abstract":["In echinoderms, the coelomic epithelium (CE) is reportedly the source of new circulating cells (coelomocytes) as well as the provider of molecular factors such as immunity-related molecules. However, its overall functions have been scarcely studied in detail. In this work, we used an integrated approach based on both microscopy (light and electron) and proteomic analyses to investigate the arm CE in the starfish Marthasterias glacialis during different physiological conditions (i.e., non-regenerating and/or regenerating). Our results show that CE cells share both ultrastructural and proteomic features with circulating coelomocytes (echinoderm immune cells). Additionally, microscopy and proteomic analyses indicate that CE cells are actively involved in protein synthesis and processing, and "],"journal":["Cell and tissue research"],"pubmed_title":["More than a simple epithelial layer: multifunctional role of echinoderm coelomic epithelium."],"pmcid":["PMC9630195"],"funding_grant_id":["POCI-01-0145-FEDER-029311","POCI-01-0145-FEDER-402-022125"],"pubmed_authors":["Varela Coelho A","Ferrario C","Anjo SI","Sugni M","Candia Carnevali MD","Bonasoro F","Manadas B","Guatelli S"],"additional_accession":[]},"is_claimable":false,"name":"More than a simple epithelial layer: multifunctional role of echinoderm coelomic epithelium.","description":"In echinoderms, the coelomic epithelium (CE) is reportedly the source of new circulating cells (coelomocytes) as well as the provider of molecular factors such as immunity-related molecules. However, its overall functions have been scarcely studied in detail. In this work, we used an integrated approach based on both microscopy (light and electron) and proteomic analyses to investigate the arm CE in the starfish Marthasterias glacialis during different physiological conditions (i.e., non-regenerating and/or regenerating). Our results show that CE cells share both ultrastructural and proteomic features with circulating coelomocytes (echinoderm immune cells). Additionally, microscopy and proteomic analyses indicate that CE cells are actively involved in protein synthesis and processing, and ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2026-05-28T03:31:35.622Z","creation":"2025-04-19T11:42:27.299Z"},"accession":"S-EPMC9630195","cross_references":{"pubmed":["36083358"],"doi":["10.1007/s00441-022-03678-x"]}}