{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lebois LAM"],"funding":["NIMH NIH HHS","U.S. Department of Health & Human Services | NIH | National Institute of Mental Health","Julia Kasparian Fund for Neuroscience Research"],"pagination":["2261-2270"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9630268"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["47(13)"],"pubmed_abstract":["Trauma-related pathological dissociation is characterized by disruptions in one's sense of self, perceptual, and affective experience. Dissociation and its trauma-related antecedents disproportionately impact women. However, despite the gender-related prevalence and high individual and societal costs, dissociation remains widely underappreciated in clinical practice. Moreover, dissociation lacks a synthesized neurobiological model across its subtypes. Leveraging the Triple Network Model of psychopathology, we sought to parse heterogeneity in dissociative experience by examining functional connectivity of three core neurocognitive networks as related to: (1) the dimensional dissociation subtypes of depersonalization/derealization and partially-dissociated intrusions; and, (2) the diagnostic"],"journal":["Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology"],"pubmed_title":["Deconstructing dissociation: a triple network model of trauma-related dissociation and its subtypes."],"pmcid":["PMC9630268"],"funding_grant_id":["K01 MH118467","R21 MH112956","R01 MH119227"],"pubmed_authors":["Nickerson LD","O'Connor L","Palermo CA","Kumar P","Robinson MA","Kaufman ML","Lebois LAM","Lewis-Schroeder N","Gruber SA","Ressler KJ","Winternitz S","Baker JT","Lambros AM","Wolff JD"],"additional_accession":[]},"is_claimable":false,"name":"Deconstructing dissociation: a triple network model of trauma-related dissociation and its subtypes.","description":"Trauma-related pathological dissociation is characterized by disruptions in one's sense of self, perceptual, and affective experience. Dissociation and its trauma-related antecedents disproportionately impact women. However, despite the gender-related prevalence and high individual and societal costs, dissociation remains widely underappreciated in clinical practice. Moreover, dissociation lacks a synthesized neurobiological model across its subtypes. Leveraging the Triple Network Model of psychopathology, we sought to parse heterogeneity in dissociative experience by examining functional connectivity of three core neurocognitive networks as related to: (1) the dimensional dissociation subtypes of depersonalization/derealization and partially-dissociated intrusions; and, (2) the diagnostic","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2026-06-03T11:55:25.127Z","creation":"2025-04-06T00:46:40.311Z"},"accession":"S-EPMC9630268","cross_references":{"pubmed":["36202907"],"doi":["10.1038/s41386-022-01468-1"]}}