biostudies-literatureUnknown12Beavis AL<h4>Introduction</h4>The human papillomavirus (HPV) vaccine is highly effective at preventing HPV-associated cancers in both males and females, yet vaccination rates remain sub-optimal in part due to vaccine hesitancy. This study sought to assess which strategies vaccine-hesitant parents perceive as most likely to motivate them to vaccinate their children against HPV.<h4>Methods</h4>In 2021, we recruited parents with children ages 10-17 years old who were not vaccinated against HPV and who felt unsure or hesitant about their decision to vaccinate their child. Participants were recruited through an online patient portal within a single institution. A screening survey assessed for vaccine hesitancy. Semi-structured interviews focused on HPV vaccine decision-making, motivators, and potential Vaccine: X100231https://www.ebi.ac.uk/biostudies/studies/S-EPMC9630772biostudies-literatureExploring HPV vaccine hesitant parents' perspectives on decision-making and motivators for vaccination.PMC9630772Adler SRositch AFMoran MBBeavis ALMeek KFleszar LfalseExploring HPV vaccine hesitant parents' perspectives on decision-making and motivators for vaccination.<h4>Introduction</h4>The human papillomavirus (HPV) vaccine is highly effective at preventing HPV-associated cancers in both males and females, yet vaccination rates remain sub-optimal in part due to vaccine hesitancy. This study sought to assess which strategies vaccine-hesitant parents perceive as most likely to motivate them to vaccinate their children against HPV.<h4>Methods</h4>In 2021, we recruited parents with children ages 10-17 years old who were not vaccinated against HPV and who felt unsure or hesitant about their decision to vaccinate their child. Participants were recruited through an online patient portal within a single institution. A screening survey assessed for vaccine hesitancy. Semi-structured interviews focused on HPV vaccine decision-making, motivators, and potential 2022-01-01T00:00:00Z2022 Dec2025-04-21T16:58:30.295Z2025-04-21T16:58:30.295ZS-EPMC96307723633783610.1016/j.jvacx.2022.100231