biostudies-literatureKong BShenzhen PhD Start-up ProgramGuangdong Basic and Applied Basic Research FoundationNational Natural Science Foundation of ChinaShanghai Municipal Commission of Health and Family PlanningNational Key Research and Development Program of ChinaShenzhen Fundamental Research ProgramScience and Technology Commission Shanghai Municipalitye2203096https://www.ebi.ac.uk/biostudies/studies/S-EPMC9631070biostudies-literatureUnknown9(31)Developing a self-reporting bioadhesive patch that has strong adhesion to the wet tissues and meanwhile can avoid adhering to the adjacent tissues is a current research difficulty and challenge. In this paper, inspired by the wet adhesion of spider web, slippery surface of Nepenthes, and structural color phenomena of chameleons, a novel structural color medical patch with surface dual-properties of wet bioadhesion and slipperiness for internal tissue repair based on inverse opal scaffold is presented. The adhesive surface made by poly(acrylic acid)-polyethylene glycol-N-hydroxysuccinimide ester and gelatin hydrogel can attain tough adhesion to internal wet tissues by absorbing tissue interfacial water and the covalent cross-linking between the hydrogel and tissue. Besides, the slippery surAdvanced science (Weinheim, Baden-Wurttemberg, Germany)Structural Color Medical Patch with Surface Dual-Properties of Wet Bioadhesion and Slipperiness.PMC96310702020A15151107802020YFA0908200JCYJ2019081315261645982101184JCYJ2021032410280902421902024RCBS20210609103713045JCYJ202103241332140382021B151512005420ZR1451800202040141Zhang DKong BGu HShang YLiu RXu WCheng YZhao YfalseStructural Color Medical Patch with Surface Dual-Properties of Wet Bioadhesion and Slipperiness.Developing a self-reporting bioadhesive patch that has strong adhesion to the wet tissues and meanwhile can avoid adhering to the adjacent tissues is a current research difficulty and challenge. In this paper, inspired by the wet adhesion of spider web, slippery surface of Nepenthes, and structural color phenomena of chameleons, a novel structural color medical patch with surface dual-properties of wet bioadhesion and slipperiness for internal tissue repair based on inverse opal scaffold is presented. The adhesive surface made by poly(acrylic acid)-polyethylene glycol-N-hydroxysuccinimide ester and gelatin hydrogel can attain tough adhesion to internal wet tissues by absorbing tissue interfacial water and the covalent cross-linking between the hydrogel and tissue. Besides, the slippery sur2022-01-01T00:00:00Z2022 Nov2025-04-05T12:33:57.447Z2025-02-19T00:31:46.369ZS-EPMC96310703608965510.1002/advs.202203096