{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(4)"],"submitter":["Giossi R"],"funding":["Postgraduate School of Clinical Pharmacology and Toxicology, Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milan, Italy"],"pubmed_abstract":["Introduction
The IASP ICD-11 chronic primary pain (CPP) definition includes 19 different painful conditions. In recent years, interest in the potential role of cannabinoids in the management of CPP has increased, since they demonstrated a possible efficacy in treating pain, especially in secondary pain conditions. However, limited evidence is available for patients with CPP. The aim of this systematic review and meta-analysis is to evaluate the efficacy and safety of cannabinoid administration in CPP.Methods
PubMed, EMBASE, and Cochrane Library were searched form the beginning up to 31 October 2021 to retrieve published articles of randomized controlled trials (RCTs) or observational, retrospective or prospective, studies, investigating cannabinoids in CPP. The study screen"],"journal":["Pain and therapy"],"pagination":["1341-1358"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9633894"],"repository":["biostudies-literature"],"pubmed_title":["Systematic Review and Meta-analysis Seem to Indicate that Cannabinoids for Chronic Primary Pain Treatment Have Limited Benefit."],"pmcid":["PMC9633894"],"pubmed_authors":["Boni G","Bilancio MC","Fittipaldo VA","Enisci S","Pani A","Padroni M","Fornasari D","Corru F","Scaglione F","Mazzari M","Tramacere I","Carrara F","Giossi R","Romio MS"],"additional_accession":[]},"is_claimable":false,"name":"Systematic Review and Meta-analysis Seem to Indicate that Cannabinoids for Chronic Primary Pain Treatment Have Limited Benefit.","description":"Introduction
The IASP ICD-11 chronic primary pain (CPP) definition includes 19 different painful conditions. In recent years, interest in the potential role of cannabinoids in the management of CPP has increased, since they demonstrated a possible efficacy in treating pain, especially in secondary pain conditions. However, limited evidence is available for patients with CPP. The aim of this systematic review and meta-analysis is to evaluate the efficacy and safety of cannabinoid administration in CPP.Methods
PubMed, EMBASE, and Cochrane Library were searched form the beginning up to 31 October 2021 to retrieve published articles of randomized controlled trials (RCTs) or observational, retrospective or prospective, studies, investigating cannabinoids in CPP. The study screen","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-22T11:19:54.914Z","creation":"2025-04-05T23:53:40.966Z"},"accession":"S-EPMC9633894","cross_references":{"pubmed":["36129666"],"doi":["10.1007/s40122-022-00434-5"]}}