biostudies-literatureNiu JPostdoctoral Start-up Science Foundation of HeilongjiangInnovation Research Project for Master Student supported by Heilongjiang Bayi Agricultural UniversityNational Key R&amp;D Program of ChinaHeilongjiang Bayi Agricultural University Support Program for San Heng San ZongNatural Science Foundation of Heilongjiang Province1695-1711https://www.ebi.ac.uk/biostudies/studies/S-EPMC9636366biostudies-literatureUnknown28(9)The C2 domain family proteins in plants has been recently shown to be involved in the response to abiotic stress such as salt and drought stress. However, less information on C2 domain family members has been reported in <i>Sorghum bicolor</i> (L.), which is a tolerant cereal crop. To elaborate the mechanism of C2 domain family members in response to abiotic stress, bioinformatic methods were used to analyze this family. The results indicated that 69 C2 domain genes belonging to 5 different groups were first identified within the sorghum genome, and each group possessed various gene structures and conserved functional domains. Second, those C2 family genes were localized on 10 chromosomes 3 tandem repeat genes and 1 pair of repeat gene fragments were detected. The family members further prPhysiology and molecular biology of plants : an international journal of functional plant biologyGenome-wide identification and characterization of the C2 domain family in <i>Sorghum bicolor</i> (L.) and expression profiles in response to saline-alkali stress.PMC9636366YJSCX2021-Y107ZRCLG201906LBH-Q191642018YFD1000702C20160462018YFD1000700YJSCX2021-Y105Li XKong LNiu TLi ZLi JDai LZhu JNiu JWu RCheng XfalseGenome-wide identification and characterization of the C2 domain family in <i>Sorghum bicolor</i> (L.) and expression profiles in response to saline-alkali stress.The C2 domain family proteins in plants has been recently shown to be involved in the response to abiotic stress such as salt and drought stress. However, less information on C2 domain family members has been reported in <i>Sorghum bicolor</i> (L.), which is a tolerant cereal crop. To elaborate the mechanism of C2 domain family members in response to abiotic stress, bioinformatic methods were used to analyze this family. The results indicated that 69 C2 domain genes belonging to 5 different groups were first identified within the sorghum genome, and each group possessed various gene structures and conserved functional domains. Second, those C2 family genes were localized on 10 chromosomes 3 tandem repeat genes and 1 pair of repeat gene fragments were detected. The family members further pr2022-01-01T00:00:00Z2022 Sep2026-05-28T01:33:13.602Z2025-04-06T16:24:53.814ZS-EPMC96363663638797910.1007/s12298-022-01222-3