{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["1244"],"submitter":["Afsar N"],"pubmed_abstract":["A new α-Tetralone based chalcone compound, (2E)-2-(4-ethoxybenzylidene)-3,4-dihydro-2H-naphthalen-1-one (<b>EBDN</b>) has been synthesized by Claisen-Schmidt condensation reaction of α-Tetralone (<b>1</b>) with 4-Ethoxybenzaldehyde (<b>2</b>) in basic medium. Then it was allowed to grow through slow evaporation solution growth technique. The molecular structure of grown <b>EBDN</b> has been systematically characterized by SCXRD, FT-IR, <sup>1</sup>H NMR and <sup>13</sup>C NMR spectroscopic studies. The micro-hardness, thermal (TGA & DTA) and photoluminence studies of the synthesized <b>EBDN</b> were also examined. The <b>EBDN</b> was screened for its anti-inflammatory, antidiabetic and anti-oxidant activity. It has shown admirable anti-inflammatory and antidiabetic activity. Protein-Ligand"],"journal":["Journal of molecular structure"],"pagination":["130967"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9637384"],"repository":["biostudies-literature"],"pubmed_title":["(<i>2E</i>)-2-(4-ethoxybenzylidene)-3,4-dihydro-<i>2H</i>-naphthalen-1-one single crystal: Synthesis, growth, crystal structure, spectral characterization, biological evaluation and binding interactions with SARS-CoV-2 main protease."],"pmcid":["PMC9637384"],"pubmed_authors":["Jonathan DR","Manivannan S","Satheesh D","Afsar N","Revathi BK"],"additional_accession":[]},"is_claimable":false,"name":"(<i>2E</i>)-2-(4-ethoxybenzylidene)-3,4-dihydro-<i>2H</i>-naphthalen-1-one single crystal: Synthesis, growth, crystal structure, spectral characterization, biological evaluation and binding interactions with SARS-CoV-2 main protease.","description":"A new α-Tetralone based chalcone compound, (2E)-2-(4-ethoxybenzylidene)-3,4-dihydro-2H-naphthalen-1-one (<b>EBDN</b>) has been synthesized by Claisen-Schmidt condensation reaction of α-Tetralone (<b>1</b>) with 4-Ethoxybenzaldehyde (<b>2</b>) in basic medium. Then it was allowed to grow through slow evaporation solution growth technique. The molecular structure of grown <b>EBDN</b> has been systematically characterized by SCXRD, FT-IR, <sup>1</sup>H NMR and <sup>13</sup>C NMR spectroscopic studies. The micro-hardness, thermal (TGA & DTA) and photoluminence studies of the synthesized <b>EBDN</b> were also examined. The <b>EBDN</b> was screened for its anti-inflammatory, antidiabetic and anti-oxidant activity. It has shown admirable anti-inflammatory and antidiabetic activity. Protein-Ligand","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-21T21:11:57.424Z","creation":"2024-12-03T20:26:47.459Z"},"accession":"S-EPMC9637384","cross_references":{"pubmed":["36373070"],"doi":["10.1016/j.molstruc.2021.130967"]}}