biostudies-literatureUnknown127(10)Aasbo G<h4>Background</h4>Cervical cancer screening participation is suboptimal in most settings. We assessed whether human papillomavirus (HPV) self-sampling may increase screening participation among long-term non-attenders in Norway.<h4>Methods</h4>A pragmatic randomised controlled trial with participation as the primary outcome was initiated in the national cervical screening programme in March 2019. A random sample of 6000 women aged 35-69 years who had not attended screening for at least 10 years were randomised 1:1:1 to receive either (i) a reminder to attend regular screening (control), (ii) an offer to order a self-sampling kit (opt-in) for HPV testing or (iii) a self-sampling kit unsolicited (send-to-all) for HPV testing.<h4>Results</h4>Total participation was 4.8%, 17.0% and 27.7% amonBritish journal of cancer1816-1826https://www.ebi.ac.uk/biostudies/studies/S-EPMC9643532biostudies-literatureHPV self-sampling among long-term non-attenders to cervical cancer screening in Norway: a pragmatic randomised controlled trial.PMC9643532Iversen GAPresthus GKTrope ACastle PEChristiansen MHUndem KChristiansen IKBaasland IHansen BTNygard MAasbo GMunk ACBjorge TfalseHPV self-sampling among long-term non-attenders to cervical cancer screening in Norway: a pragmatic randomised controlled trial.<h4>Background</h4>Cervical cancer screening participation is suboptimal in most settings. We assessed whether human papillomavirus (HPV) self-sampling may increase screening participation among long-term non-attenders in Norway.<h4>Methods</h4>A pragmatic randomised controlled trial with participation as the primary outcome was initiated in the national cervical screening programme in March 2019. A random sample of 6000 women aged 35-69 years who had not attended screening for at least 10 years were randomised 1:1:1 to receive either (i) a reminder to attend regular screening (control), (ii) an offer to order a self-sampling kit (opt-in) for HPV testing or (iii) a self-sampling kit unsolicited (send-to-all) for HPV testing.<h4>Results</h4>Total participation was 4.8%, 17.0% and 27.7% amon2022-01-01T00:00:00Z2022 Nov2026-05-28T01:07:46.154Z2025-04-19T22:47:01.612ZS-EPMC96435323599593610.1038/s41416-022-01954-9