biostudies-literatureUnknown101(44)Obinata DWe performed a retrospective study to clarify the characteristics of prostate biopsies in patients treated with dutasteride, a benign prostate hyperplasia treatment drug that inhibits 5α-reductase. We studied the digital clinical data of 677 patients, including 96 cases treated with dutasteride, with suspected localized prostate cancer. All patients underwent transrectal ultrasonography-guided prostate biopsy between 2014 and 2017 in our department. A propensity score matching analysis was performed based on prostate-specific antigen (PSA) (calculated as double the PSA value for the dutasteride group) and age. Ninety-six patients in each of the dutasteride and control groups were assessed and their characteristics were compared. The characteristics of the patients in the dutasteride and coMedicinee31658https://www.ebi.ac.uk/biostudies/studies/S-EPMC9646501biostudies-literatureCharacteristics of prostate biopsy in patients under the dutasteride treatment.PMC9646501Nakahara KTakahashi SMochida JObinata DYoshizawa TYamaguchi KfalseCharacteristics of prostate biopsy in patients under the dutasteride treatment.We performed a retrospective study to clarify the characteristics of prostate biopsies in patients treated with dutasteride, a benign prostate hyperplasia treatment drug that inhibits 5α-reductase. We studied the digital clinical data of 677 patients, including 96 cases treated with dutasteride, with suspected localized prostate cancer. All patients underwent transrectal ultrasonography-guided prostate biopsy between 2014 and 2017 in our department. A propensity score matching analysis was performed based on prostate-specific antigen (PSA) (calculated as double the PSA value for the dutasteride group) and age. Ninety-six patients in each of the dutasteride and control groups were assessed and their characteristics were compared. The characteristics of the patients in the dutasteride and co2022-01-01T00:00:00Z2022 Nov2025-04-05T12:31:59.136Z2025-04-05T12:31:59.136ZS-EPMC96465013634308210.1097/MD.0000000000031658