{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Kim K"],"pubmed_abstract":["<h4>Background</h4>Studies on the risk and protective factors for lung function decline and mortality in rheumatoid arthritis-related interstitial lung disease (RA-ILD) are limited.<h4>Objectives</h4>We aimed to investigate clinical factors and medication uses associated with lung function decline and mortality in RA-ILD.<h4>Methods</h4>This retrospective cohort study examined the medical records of patients with RA-ILD who visited Severance Hospital between January 2006 and December 2019. We selected 170 patients with RA-ILD who had undergone at least one spirometry test and chest computed tomography scan. An absolute decline of ⩾10% in the functional vital capacity (FVC) was defined as significant decline in pulmonary function. Data for analysis were retrieved from electronic medical rec"],"journal":["Therapeutic advances in respiratory disease"],"pagination":["17534666221135314"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9647291"],"repository":["biostudies-literature"],"pubmed_title":["Protective effect of methotrexate on lung function and mortality in rheumatoid arthritis-related interstitial lung disease: a retrospective cohort study."],"pmcid":["PMC9647291"],"pubmed_authors":["Kim SY","Leem AY","Chung KS","Woo A","Lee SH","Kim K","Park MS","Kang YA","Kim EY","Park Y","Yong SH","Jung JY","Kim YS"],"additional_accession":[]},"is_claimable":false,"name":"Protective effect of methotrexate on lung function and mortality in rheumatoid arthritis-related interstitial lung disease: a retrospective cohort study.","description":"<h4>Background</h4>Studies on the risk and protective factors for lung function decline and mortality in rheumatoid arthritis-related interstitial lung disease (RA-ILD) are limited.<h4>Objectives</h4>We aimed to investigate clinical factors and medication uses associated with lung function decline and mortality in RA-ILD.<h4>Methods</h4>This retrospective cohort study examined the medical records of patients with RA-ILD who visited Severance Hospital between January 2006 and December 2019. We selected 170 patients with RA-ILD who had undergone at least one spirometry test and chest computed tomography scan. An absolute decline of ⩾10% in the functional vital capacity (FVC) was defined as significant decline in pulmonary function. Data for analysis were retrieved from electronic medical rec","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan-Dec","modification":"2025-04-19T10:40:09.889Z","creation":"2025-04-19T10:40:09.889Z"},"accession":"S-EPMC9647291","cross_references":{"pubmed":["36346076"],"doi":["10.1177/17534666221135314"]}}