biostudies-literatureUnknown7(44)Kohlan TBPoly(2-oxazoline)s (POZs) are widely investigated for their applications in various fields due to their unique properties. To exploit and combine different characteristics of the POZ family, 2-oxazoline monomers can be copolymerized to prepare tailor-made copolymers with the desired glass transition temperature (<i>T</i> _g), melting temperature (<i>T</i> _m), amphiphilicity, and functionality. Here, we report the synthesis and characterization of 2-oxazoline monomers and a range of POZ copolymers produced, thereof. 2-Propyl-2-oxazoline (PrOZ) and 2-pentyl-2-oxazoline (PeOZ) monomers were synthesized by two different methods starting from nitriles or carboxylic acids. A number of POZ copolymers were synthesized by copolymerization of 2-ethyl-2-oxazoline (EOZ) with eitheACS omega40067-40077https://www.ebi.ac.uk/biostudies/studies/S-EPMC9648074biostudies-literatureSynthesis and Structure-Property Relationship of Amphiphilic Poly(2-ethyl-<i>co</i>-2-(alkyl/aryl)-2-oxazoline) Copolymers.PMC9648074Unal SKohlan TBYildiz MAtespare AEMenceloglu YZDizman BfalseSynthesis and Structure-Property Relationship of Amphiphilic Poly(2-ethyl-<i>co</i>-2-(alkyl/aryl)-2-oxazoline) Copolymers.Poly(2-oxazoline)s (POZs) are widely investigated for their applications in various fields due to their unique properties. To exploit and combine different characteristics of the POZ family, 2-oxazoline monomers can be copolymerized to prepare tailor-made copolymers with the desired glass transition temperature (<i>T</i> _g), melting temperature (<i>T</i> _m), amphiphilicity, and functionality. Here, we report the synthesis and characterization of 2-oxazoline monomers and a range of POZ copolymers produced, thereof. 2-Propyl-2-oxazoline (PrOZ) and 2-pentyl-2-oxazoline (PeOZ) monomers were synthesized by two different methods starting from nitriles or carboxylic acids. A number of POZ copolymers were synthesized by copolymerization of 2-ethyl-2-oxazoline (EOZ) with eithe2022-01-01T00:00:00Z2022 Nov2025-04-05T11:35:56.198Z2025-04-05T11:35:56.198ZS-EPMC96480743638586010.1021/acsomega.2c04809