biostudies-literatureUnknown279(12)De Luca PUniversità degli Studi di Salerno<h4>Objectives</h4>To analyze the demographic data, surgical and adjuvant treatment data and the survival outcomes in adult patients affected by acinic cell carcinoma of the parotid gland (AciCC).<h4>Methods</h4>A retrospective multicenter analysis of patients treated for AciCC of the parotid gland from 2000 to 2021 was performed. Exclusion criteria were pediatric (0-18 years) patients, the absence of follow-up and patients with secondary metastatic disease to the parotid gland. Multivariable logistic regression was used to determine factors associated with survival.<h4>Results</h4>The study included 81 adult patients with AciCC of the parotid gland. The median age was 46.3 years (SD 15.81, range 19-84 years), with a gender female prevalence (F = 48, M = 33). The mean follow-up was 77.7 moEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery5821-5829https://www.ebi.ac.uk/biostudies/studies/S-EPMC9649501biostudies-literatureAcinic cell carcinoma of the parotid gland: Timeo Danaos et dona ferentes? A multicenter retrospective analysis focusing on survival outcome.PMC9649501Iemma MVigili MGPellini RRicciardiello FDallan ITogo GSalzano FAColangeli RDe Luca PRadici MSalzano GIonna Fde Campora LPetruzzi Gde Campora ECassano MEsposito EAtturo FPresutti LMolinari GCondorelli PRaso FCamaioni AD'Ecclesia ALo Manto ACintoli GFermi MAbeshi ATassone DDi Stadio AMagaldi LfalseAcinic cell carcinoma of the parotid gland: Timeo Danaos et dona ferentes? A multicenter retrospective analysis focusing on survival outcome.<h4>Objectives</h4>To analyze the demographic data, surgical and adjuvant treatment data and the survival outcomes in adult patients affected by acinic cell carcinoma of the parotid gland (AciCC).<h4>Methods</h4>A retrospective multicenter analysis of patients treated for AciCC of the parotid gland from 2000 to 2021 was performed. Exclusion criteria were pediatric (0-18 years) patients, the absence of follow-up and patients with secondary metastatic disease to the parotid gland. Multivariable logistic regression was used to determine factors associated with survival.<h4>Results</h4>The study included 81 adult patients with AciCC of the parotid gland. The median age was 46.3 years (SD 15.81, range 19-84 years), with a gender female prevalence (F = 48, M = 33). The mean follow-up was 77.7 mo2022-01-01T00:00:00Z2022 Dec2025-04-19T10:40:24.208Z2025-04-19T10:40:24.208ZS-EPMC96495013567887410.1007/s00405-022-07481-w