biostudies-literatureUnknown13Heinen J<h4>Introduction</h4>Cancer-affected patients experience high distress due to various burdens. One way to expand psycho-oncological support is through digital interventions. This protocol describes the development and structure of a web-based psycho-oncological intervention, the Make It Training optimized. This intervention is currently evaluated in the Reduct trial, a multicenter randomized controlled trial.<h4>Methods</h4>The Make It Training optimized was developed in six steps: A patient need and demand assessment, development and acceptability analysis of a prototype, the formation of a patient advisory council, the revision of the training, implementation into a web app, and the development of a motivation and evaluation plan.<h4>Results</h4>Through a process of establishing cancer-aFrontiers in psychiatry1037158https://www.ebi.ac.uk/biostudies/studies/S-EPMC9650647biostudies-literatureMindfulness and skills-based eHealth intervention to reduce distress in cancer-affected patients in the Reduct trial: Intervention protocol of the make it training optimized.PMC9650647Heinen JJansen CGraf JSchug CKruse JBeckord JDinkel APantforder MKrakowczyk JBStrunk SEMehnert-Theuerkauf AStengel ADries SWieser AErim YZipfel SWiltink JTeufel MWunsch ABauerle AfalseMindfulness and skills-based eHealth intervention to reduce distress in cancer-affected patients in the Reduct trial: Intervention protocol of the make it training optimized.<h4>Introduction</h4>Cancer-affected patients experience high distress due to various burdens. One way to expand psycho-oncological support is through digital interventions. This protocol describes the development and structure of a web-based psycho-oncological intervention, the Make It Training optimized. This intervention is currently evaluated in the Reduct trial, a multicenter randomized controlled trial.<h4>Methods</h4>The Make It Training optimized was developed in six steps: A patient need and demand assessment, development and acceptability analysis of a prototype, the formation of a patient advisory council, the revision of the training, implementation into a web app, and the development of a motivation and evaluation plan.<h4>Results</h4>Through a process of establishing cancer-a2022-01-01T00:00:00Z20222025-04-05T11:36:02.723Z2025-04-05T11:36:02.723ZS-EPMC96506473638700410.3389/fpsyt.2022.1037158