{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["18(1)"],"submitter":["Aguilar-Garcia D"],"funding":["García-Cugat foundation for biomedical research"],"pubmed_abstract":["The purpose of this study was to perform a histological and biochemical evaluation of the influence of plasma rich in growth factors (PRGF) on muscle regeneration process after a surgically induced grade II muscle laceration. A randomized, single blind, controlled experimental research was conducted including twenty-one adult healthy sheep, randomly divided in three groups (n = 7). A grade II surgical section was performed in the biceps femoris muscle of both hindlimbs. After two days (basal time), intralesional infiltration of autologous PRGF or Saline solution was randomly administered in both hindlimbs. Treatment was repeated once a week. Animal groups were euthanized at 1 (T1), 2 (T2) or 4 (T4) weeks. Histological assessment showed that PRGF intralesional injection induced a significan"],"journal":["BMC veterinary research"],"pagination":["400"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9652891"],"repository":["biostudies-literature"],"pubmed_title":["Histological and biochemical evaluation of plasma rich in growth factors treatment for grade II muscle injuries in sheep."],"pmcid":["PMC9652891"],"pubmed_authors":["Fernandez-Sarmiento JA","Poveda JMC","Castaneda JM","Bertomeu RC","Ruiz YM","Dominguez Perez JM","Rodriguez JM","Rascon PM","Del Mar Granados Machuca M","Aguilar-Garcia D","Calvo RN"],"additional_accession":[]},"is_claimable":false,"name":"Histological and biochemical evaluation of plasma rich in growth factors treatment for grade II muscle injuries in sheep.","description":"The purpose of this study was to perform a histological and biochemical evaluation of the influence of plasma rich in growth factors (PRGF) on muscle regeneration process after a surgically induced grade II muscle laceration. A randomized, single blind, controlled experimental research was conducted including twenty-one adult healthy sheep, randomly divided in three groups (n = 7). A grade II surgical section was performed in the biceps femoris muscle of both hindlimbs. After two days (basal time), intralesional infiltration of autologous PRGF or Saline solution was randomly administered in both hindlimbs. Treatment was repeated once a week. Animal groups were euthanized at 1 (T1), 2 (T2) or 4 (T4) weeks. Histological assessment showed that PRGF intralesional injection induced a significan","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-22T05:36:44.363Z","creation":"2025-04-05T21:26:10.069Z"},"accession":"S-EPMC9652891","cross_references":{"pubmed":["36371198"],"doi":["10.1186/s12917-022-03491-2"]}}