biostudies-literatureUnknown12(21)Rawicka A<h4>Background</h4>Extramedullary plasmacytoma (EMP) is a plasma cell tumor that is very rarely reported in ocular and adnexal tissue and is usually solitary and benign.<h4>Methods</h4>This study evaluated seven cases from different ophthalmology referrals submitted for histopathological analysis between 2013 and 2022.<h4>Results</h4>EMPs were diagnosed in a 9-year-old domestic short-haired cat and in six dogs (median age, 10 years): three English Cocker Spaniels, a Golden Retriever, a Maltese, and a Pinscher. EMPs affected the third eyelid conjunctiva in five cases (5/7), followed by the superior bulbar (1/7) and palpebral conjunctivae (1/7), respectively, and were presented mostly as well-defined, salmon-colored nodules. Histopathologically, the masses were composed of sheets and packetsAnimals : an open access journal from MDPI3015https://www.ebi.ac.uk/biostudies/studies/S-EPMC9653729biostudies-literatureConjunctival Extramedullary Plasmacytoma in Dogs and a Cat: Clinical Characteristics and Histopathological Findings.PMC9653729Rondena MMultari DPeruccio CGiudice CRawicka ACrasta MD'Anna NGuandalini AfalseConjunctival Extramedullary Plasmacytoma in Dogs and a Cat: Clinical Characteristics and Histopathological Findings.<h4>Background</h4>Extramedullary plasmacytoma (EMP) is a plasma cell tumor that is very rarely reported in ocular and adnexal tissue and is usually solitary and benign.<h4>Methods</h4>This study evaluated seven cases from different ophthalmology referrals submitted for histopathological analysis between 2013 and 2022.<h4>Results</h4>EMPs were diagnosed in a 9-year-old domestic short-haired cat and in six dogs (median age, 10 years): three English Cocker Spaniels, a Golden Retriever, a Maltese, and a Pinscher. EMPs affected the third eyelid conjunctiva in five cases (5/7), followed by the superior bulbar (1/7) and palpebral conjunctivae (1/7), respectively, and were presented mostly as well-defined, salmon-colored nodules. Histopathologically, the masses were composed of sheets and packets2022-01-01T00:00:00Z2022 Nov2025-04-22T19:00:15.923Z2025-04-06T02:39:52.743ZS-EPMC96537293635913910.3390/ani12213015