{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang D"],"funding":["Liaocheng University fund","ShandongProvincial Natural Science Foundation"],"pagination":["7392"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9656399"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(21)"],"pubmed_abstract":["The efficient \"One-pot\" CuCl<sub>2</sub>-catalyzed C-S bond coupling reactions were developed for the synthesis of dibenzo[<i>b</i>,<i>f</i>][1,4]thiazepines and 11-methy-ldibenzo[<i>b</i>,<i>f</i>][1,4]thiazepines via 2-iodobenzaldehydes/2-iodoacetophenones with 2-aminobenzenethiols/2,2'-disulfanediyldianilines by using bifunctional-reagent N, N'-dimethylethane-1,2-diamine (DMEDA), which worked as ligand and reductant. The reactions were compatible with a range of substrates to give the corresponding products in moderate to excellent yields."],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["\"One-Pot\" CuCl<sub>2</sub>-Mediated Condensation/C-S Bond Coupling Reactions to Synthesize Dibenzothiazepines by Bi-Functional-Reagent N, N'-Dimethylethane-1,2-Diamine."],"pmcid":["PMC9656399"],"funding_grant_id":["318051403","ZR2019QB022"],"pubmed_authors":["Li Z","Wang D","Fang C","Liu R","Yang B","Lu Q","Shen G"],"additional_accession":[]},"is_claimable":false,"name":"\"One-Pot\" CuCl<sub>2</sub>-Mediated Condensation/C-S Bond Coupling Reactions to Synthesize Dibenzothiazepines by Bi-Functional-Reagent N, N'-Dimethylethane-1,2-Diamine.","description":"The efficient \"One-pot\" CuCl<sub>2</sub>-catalyzed C-S bond coupling reactions were developed for the synthesis of dibenzo[<i>b</i>,<i>f</i>][1,4]thiazepines and 11-methy-ldibenzo[<i>b</i>,<i>f</i>][1,4]thiazepines via 2-iodobenzaldehydes/2-iodoacetophenones with 2-aminobenzenethiols/2,2'-disulfanediyldianilines by using bifunctional-reagent N, N'-dimethylethane-1,2-diamine (DMEDA), which worked as ligand and reductant. The reactions were compatible with a range of substrates to give the corresponding products in moderate to excellent yields.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-22T12:34:58.765Z","creation":"2025-04-06T00:21:28.201Z"},"accession":"S-EPMC9656399","cross_references":{"pubmed":["36364217"],"doi":["10.3390/molecules27217392"]}}