biostudies-literatureWang DLiaocheng University fundShandongProvincial Natural Science Foundation7392https://www.ebi.ac.uk/biostudies/studies/S-EPMC9656399biostudies-literatureUnknown27(21)The efficient "One-pot" CuCl₂-catalyzed C-S bond coupling reactions were developed for the synthesis of dibenzo[<i>b</i>,<i>f</i>][1,4]thiazepines and 11-methy-ldibenzo[<i>b</i>,<i>f</i>][1,4]thiazepines via 2-iodobenzaldehydes/2-iodoacetophenones with 2-aminobenzenethiols/2,2'-disulfanediyldianilines by using bifunctional-reagent N, N'-dimethylethane-1,2-diamine (DMEDA), which worked as ligand and reductant. The reactions were compatible with a range of substrates to give the corresponding products in moderate to excellent yields.Molecules (Basel, Switzerland)"One-Pot" CuCl₂-Mediated Condensation/C-S Bond Coupling Reactions to Synthesize Dibenzothiazepines by Bi-Functional-Reagent N, N'-Dimethylethane-1,2-Diamine.PMC9656399318051403ZR2019QB022Li ZWang DFang CLiu RYang BLu QShen Gfalse"One-Pot" CuCl₂-Mediated Condensation/C-S Bond Coupling Reactions to Synthesize Dibenzothiazepines by Bi-Functional-Reagent N, N'-Dimethylethane-1,2-Diamine.The efficient "One-pot" CuCl₂-catalyzed C-S bond coupling reactions were developed for the synthesis of dibenzo[<i>b</i>,<i>f</i>][1,4]thiazepines and 11-methy-ldibenzo[<i>b</i>,<i>f</i>][1,4]thiazepines via 2-iodobenzaldehydes/2-iodoacetophenones with 2-aminobenzenethiols/2,2'-disulfanediyldianilines by using bifunctional-reagent N, N'-dimethylethane-1,2-diamine (DMEDA), which worked as ligand and reductant. The reactions were compatible with a range of substrates to give the corresponding products in moderate to excellent yields.2022-01-01T00:00:00Z2022 Oct2025-04-22T12:34:58.765Z2025-04-06T00:21:28.201ZS-EPMC96563993636421710.3390/molecules27217392