biostudies-literatureUnknown27(21)Sabira OThe unpredictable invasion of the Mupli beetle, <i>Luprops tristis</i> Fabricius (Coleoptera: Tenebrionidae), makes areas uninhabitable to humans. These beetles produce a strong-smelling, irritating secretion as a defence mechanism, which causes blisters on contact with human skin. In the current study, gas chromatography high-resolution mass spectrometry (GC-HRMS) analysis of the defensive gland extract of the Mupli beetle revealed the presence of compounds such as 2,3,dimethyl-1,4-benzoquinone, 1,3-dihydroxy-2-methylbenzene, 2,5-dimethyl hydroquinone, tetracosane, oleic acid, hexacosane, pentacosane, 7-hexadecenal and tert-hexadecanethiol. The defensive gland extracts showed considerable antibacterial activity on Gram-negative and Gram-positive bacteria in an agar diffusion assay. The chMolecules (Basel, Switzerland)7476https://www.ebi.ac.uk/biostudies/studies/S-EPMC9657179biostudies-literatureThe Chemical Composition and Antimitotic, Antioxidant, Antibacterial and Cytotoxic Properties of the Defensive Gland Extract of the Beetle, <i>Luprops tristis</i> Fabricius.PMC9657179Vignesh ARRasheed VAVarma SRNikhila KJayaraj KNSebastin MSabira OBabu AAjaykumar APBinitha VSVasu ZKSujith MSfalseThe Chemical Composition and Antimitotic, Antioxidant, Antibacterial and Cytotoxic Properties of the Defensive Gland Extract of the Beetle, <i>Luprops tristis</i> Fabricius.The unpredictable invasion of the Mupli beetle, <i>Luprops tristis</i> Fabricius (Coleoptera: Tenebrionidae), makes areas uninhabitable to humans. These beetles produce a strong-smelling, irritating secretion as a defence mechanism, which causes blisters on contact with human skin. In the current study, gas chromatography high-resolution mass spectrometry (GC-HRMS) analysis of the defensive gland extract of the Mupli beetle revealed the presence of compounds such as 2,3,dimethyl-1,4-benzoquinone, 1,3-dihydroxy-2-methylbenzene, 2,5-dimethyl hydroquinone, tetracosane, oleic acid, hexacosane, pentacosane, 7-hexadecenal and tert-hexadecanethiol. The defensive gland extracts showed considerable antibacterial activity on Gram-negative and Gram-positive bacteria in an agar diffusion assay. The ch2022-01-01T00:00:00Z2022 Nov2025-04-25T23:29:43.159Z2025-04-06T09:22:02.552ZS-EPMC96571793636430310.3390/molecules27217476