biostudies-literatureUnknown11(21)Said M<h4>Objective</h4>Previous reports indicate a negative impact of anemia on the outcome of an aneurysmal subarachnoid hemorrhage (SAH). We aimed to identify the outcome-relevant severity of post-SAH anemia.<h4>Methods</h4>SAH cases treated at our institution between 01/2005 and 06/2016 were included (<i>n</i> = 640). The onset, duration, and severity (nadir hemoglobin (nHB) level) of anemia during the initial hospital stay were recorded. Study endpoints were new cerebral infarctions, a poor outcome six months post-SAH (modified Rankin scale &gt; 3), and in-hospital mortality. To assess independent associations with the study endpoints, different multivariable regression models were performed, adjusted for relevant patient and baseline SAH characteristics as well as anemia-associated clinicaJournal of clinical medicine6258https://www.ebi.ac.uk/biostudies/studies/S-EPMC9657573biostudies-literatureImpact of Anemia Severity on the Outcome of an Aneurysmal Subarachnoid Hemorrhage.PMC9657573Sure UChihi MDammann PWrede KHLenz VJabbarli RUerschels AKGumus MDinger TFRodemerk JSaid MOppong MDRauschenbach LfalseImpact of Anemia Severity on the Outcome of an Aneurysmal Subarachnoid Hemorrhage.<h4>Objective</h4>Previous reports indicate a negative impact of anemia on the outcome of an aneurysmal subarachnoid hemorrhage (SAH). We aimed to identify the outcome-relevant severity of post-SAH anemia.<h4>Methods</h4>SAH cases treated at our institution between 01/2005 and 06/2016 were included (<i>n</i> = 640). The onset, duration, and severity (nadir hemoglobin (nHB) level) of anemia during the initial hospital stay were recorded. Study endpoints were new cerebral infarctions, a poor outcome six months post-SAH (modified Rankin scale &gt; 3), and in-hospital mortality. To assess independent associations with the study endpoints, different multivariable regression models were performed, adjusted for relevant patient and baseline SAH characteristics as well as anemia-associated clinica2022-01-01T00:00:00Z2022 Oct2025-04-25T23:38:21.883Z2025-04-06T09:24:42.577ZS-EPMC96575733636248610.3390/jcm11216258