{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(21)"],"submitter":["Larrue R"],"pubmed_abstract":["MicroRNAs (miRNAs) are small, non-coding RNA species that control gene expression and confer robustness to biological processes. Over the last two decades, their important roles during kidney development, homeostasis and the treatment of diseases have been established, in particular during the onset and progression of various forms of acute and chronic renal disorders. In recent years, miR-21, one of the best-characterized miRNAs to date, has received much attention in renal physiology in particular given its high degree of conservation and expression in kidneys, as well as its potent pathogenic role in various debilitating renal diseases. This review summarizes the current knowledge on miR-21's involvement in both renal homeostasis and diseases, in particular its double-edged-sword role i"],"journal":["Cells"],"pagination":["3525"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9657972"],"repository":["biostudies-literature"],"pubmed_title":["The Versatile Role of miR-21 in Renal Homeostasis and Diseases."],"pmcid":["PMC9657972"],"pubmed_authors":["Perrais M","Lionet A","Glowacki F","Pottier N","Hennino MF","Fellah S","Cauffiez C","Larrue R","Van der Hauwaert C"],"additional_accession":[]},"is_claimable":false,"name":"The Versatile Role of miR-21 in Renal Homeostasis and Diseases.","description":"MicroRNAs (miRNAs) are small, non-coding RNA species that control gene expression and confer robustness to biological processes. Over the last two decades, their important roles during kidney development, homeostasis and the treatment of diseases have been established, in particular during the onset and progression of various forms of acute and chronic renal disorders. In recent years, miR-21, one of the best-characterized miRNAs to date, has received much attention in renal physiology in particular given its high degree of conservation and expression in kidneys, as well as its potent pathogenic role in various debilitating renal diseases. This review summarizes the current knowledge on miR-21's involvement in both renal homeostasis and diseases, in particular its double-edged-sword role i","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-25T23:32:53.568Z","creation":"2025-04-06T09:22:39.616Z"},"accession":"S-EPMC9657972","cross_references":{"pubmed":["36359921"],"doi":["10.3390/cells11213525"]}}