biostudies-literatureUnknown9Dludla PV<h4>Background</h4>Vitamin C is one of the most consumed dietary compounds and contains abundant antioxidant properties that could be essential in improving metabolic function. Thus, the current systematic review analyzed evidence on the beneficial effects of vitamin C intake on cardiovascular disease (CVD)-related outcomes in patients with diabetes or metabolic syndrome.<h4>Methods</h4>To identify relevant randomized control trials (RCTs), a systematic search was run using prominent search engines like PubMed and Google Scholar, from beginning up to March 2022. The modified Black and Downs checklist was used to assess the quality of evidence.<h4>Results</h4>Findings summarized in the current review favor the beneficial effects of vitamin C intake on improving basic metabolic parameters anFrontiers in nutrition1011002https://www.ebi.ac.uk/biostudies/studies/S-EPMC9659906biostudies-literatureVitamin C intake potentially lowers total cholesterol to improve endothelial function in diabetic patients at increased risk of cardiovascular disease: A systematic review of randomized controlled trials.PMC9659906Basson AKMxinwa VMokgalaboni KSabbatinelli JDludla PVNkambule BBHanser SNyambuya TMMazibuko-Mbeje SENdevahoma FZiqubu KTiano LMabhida SEfalseVitamin C intake potentially lowers total cholesterol to improve endothelial function in diabetic patients at increased risk of cardiovascular disease: A systematic review of randomized controlled trials.<h4>Background</h4>Vitamin C is one of the most consumed dietary compounds and contains abundant antioxidant properties that could be essential in improving metabolic function. Thus, the current systematic review analyzed evidence on the beneficial effects of vitamin C intake on cardiovascular disease (CVD)-related outcomes in patients with diabetes or metabolic syndrome.<h4>Methods</h4>To identify relevant randomized control trials (RCTs), a systematic search was run using prominent search engines like PubMed and Google Scholar, from beginning up to March 2022. The modified Black and Downs checklist was used to assess the quality of evidence.<h4>Results</h4>Findings summarized in the current review favor the beneficial effects of vitamin C intake on improving basic metabolic parameters an2022-01-01T00:00:00Z20222025-04-22T12:38:50.778Z2025-04-06T00:19:29.897ZS-EPMC96599063638690710.3389/fnut.2022.1011002