{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["O'Connell A"],"pubmed_abstract":["Red rot caused by the fungus <i>Colletotrichum falcatum</i> is the main disease limiting sugarcane productivity in several countries including the major producer India. The genetic basis for red rot resistance is unclear. We studied a panel of 305 sugarcane clones from the Australian breeding program for disease response phenotype and genotype using an Affymetrix<sup>®</sup> Axiom<sup>®</sup> array, to better understand the genetic basis of red rot resistance. SNP markers highly significantly associated with red rot response (≤ 10<sup>-8</sup>) were identified. Markers with largest effect were located in a single 14.6 Mb genomic region of sorghum (the closest diploid relative of sugarcane with a sequenced genome) suggesting the presence of a major-effect QTL. By genomic selection, the esti"],"journal":["Frontiers in plant science"],"pagination":["1021182"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9660812"],"repository":["biostudies-literature"],"pubmed_title":["Combining genomic selection with genome-wide association analysis identified a large-effect QTL and improved selection for red rot resistance in sugarcane."],"pmcid":["PMC9660812"],"pubmed_authors":["Mohanraj K","O'Connell A","Jackson P","Ram B","Lakshmanan P","Deo J","Aitken KS","Viswanathan R","Deomano E","Wei X","Manimekalai R","Hemaprabha G"],"additional_accession":[]},"is_claimable":false,"name":"Combining genomic selection with genome-wide association analysis identified a large-effect QTL and improved selection for red rot resistance in sugarcane.","description":"Red rot caused by the fungus <i>Colletotrichum falcatum</i> is the main disease limiting sugarcane productivity in several countries including the major producer India. The genetic basis for red rot resistance is unclear. We studied a panel of 305 sugarcane clones from the Australian breeding program for disease response phenotype and genotype using an Affymetrix<sup>®</sup> Axiom<sup>®</sup> array, to better understand the genetic basis of red rot resistance. SNP markers highly significantly associated with red rot response (≤ 10<sup>-8</sup>) were identified. Markers with largest effect were located in a single 14.6 Mb genomic region of sorghum (the closest diploid relative of sugarcane with a sequenced genome) suggesting the presence of a major-effect QTL. By genomic selection, the esti","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-19T13:24:27.98Z","creation":"2025-04-19T13:24:27.98Z"},"accession":"S-EPMC9660812","cross_references":{"pubmed":["36388469"],"doi":["10.3389/fpls.2022.1021182"]}}