{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Haines MC"],"funding":["UK Research and Innovation","Engineering and Physical Sciences Research Council"],"pagination":["ysac023"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9664905"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(1)"],"pubmed_abstract":["Standardized deoxyribonucleic acid (DNA) assembly methods utilizing modular components provide a powerful framework to explore designs and iterate through Design-Build-Test-Learn cycles. Biopart Assembly Standard for Idempotent Cloning (BASIC) DNA assembly uses modular parts and linkers, is highly accurate, easy to automate, free for academic and commercial use and enables hierarchical assemblies through an idempotent format. These features enable applications including pathway engineering, ribosome binding site (RBS) tuning, fusion protein engineering and multiplexed guide ribonucleic acid (RNA) expression. In this work, we present basicsynbio, open-source software encompassing a Web App (https://basicsynbio.web.app/) and Python Package (https://github.com/LondonBiofoundry/basicsynbio), e"],"journal":["Synthetic biology (Oxford, England)"],"pubmed_title":["basicsynbio and the BASIC SEVA collection: software and vectors for an established DNA assembly method."],"pmcid":["PMC9664905"],"funding_grant_id":["EP/R034915/1","EP/T013788/1"],"pubmed_authors":["Marshall J","Baldwin GS","Haines MC","Storch M","Shenshin VA","Carling B","Freemont P"],"additional_accession":[]},"is_claimable":false,"name":"basicsynbio and the BASIC SEVA collection: software and vectors for an established DNA assembly method.","description":"Standardized deoxyribonucleic acid (DNA) assembly methods utilizing modular components provide a powerful framework to explore designs and iterate through Design-Build-Test-Learn cycles. Biopart Assembly Standard for Idempotent Cloning (BASIC) DNA assembly uses modular parts and linkers, is highly accurate, easy to automate, free for academic and commercial use and enables hierarchical assemblies through an idempotent format. These features enable applications including pathway engineering, ribosome binding site (RBS) tuning, fusion protein engineering and multiplexed guide ribonucleic acid (RNA) expression. In this work, we present basicsynbio, open-source software encompassing a Web App (https://basicsynbio.web.app/) and Python Package (https://github.com/LondonBiofoundry/basicsynbio), e","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T00:36:48.962Z","creation":"2025-04-04T00:36:48.962Z"},"accession":"S-EPMC9664905","cross_references":{"pubmed":["36381610"],"doi":["10.1093/synbio/ysac023"]}}