{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kufa T"],"funding":["Medical Research Council","National Department of Health, Republic of South Africa","National Department of Health"],"pagination":["34-47"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9664941"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(1)"],"pubmed_abstract":["<h4>Introduction</h4>We describe epidemiology and outcomes of confirmed SARS-CoV-2 infection and positive admissions among children <18 years in South Africa, an upper-middle income setting with high inequality.<h4>Methods</h4>Laboratory and hospital COVID-19 surveillance data, 28 January - 19 September 2020 was used. Testing rates were calculated as number of tested for SARS-CoV-2 divided by population at risk; test positivity rates were calculated as positive tests divided by total number of tests. In-hospital case fatality ratio (CFR) was calculated based on hospitalized positive admissions with outcome data who died in-hospital and whose death was judged SARS-CoV-2 related by attending physician.<h4>Findings</h4>315 570 children aged <18 years were tested for SARS-CoV-2; representing 8"],"journal":["Influenza and other respiratory viruses"],"pubmed_title":["Epidemiology of SARS-CoV-2 infection and SARS-CoV-2 positive hospital admissions among children in South Africa."],"pmcid":["PMC9664941"],"funding_grant_id":["MR/V028782/1"],"pubmed_authors":["Shuping L","Mathema H","Manana PN","Dangor Z","Bapela P","Verwey C","Madhi SA","Blumberg L","Shonhiwa AM","Hunt G","von Gottburg A","Ntshoe G","Maruma W","Walaza S","Kufa T","Ebonwu J","Zar HJ","Saloojee H","Tempia S","Wolter N","Masha M","Jassat W","Ndhlovu N","Govender NP","Modise M","Cohen C","Moore D"],"additional_accession":[]},"is_claimable":false,"name":"Epidemiology of SARS-CoV-2 infection and SARS-CoV-2 positive hospital admissions among children in South Africa.","description":"<h4>Introduction</h4>We describe epidemiology and outcomes of confirmed SARS-CoV-2 infection and positive admissions among children <18 years in South Africa, an upper-middle income setting with high inequality.<h4>Methods</h4>Laboratory and hospital COVID-19 surveillance data, 28 January - 19 September 2020 was used. Testing rates were calculated as number of tested for SARS-CoV-2 divided by population at risk; test positivity rates were calculated as positive tests divided by total number of tests. In-hospital case fatality ratio (CFR) was calculated based on hospitalized positive admissions with outcome data who died in-hospital and whose death was judged SARS-CoV-2 related by attending physician.<h4>Findings</h4>315 570 children aged <18 years were tested for SARS-CoV-2; representing 8","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-04-05T15:42:15.295Z","creation":"2025-04-05T15:42:15.295Z"},"accession":"S-EPMC9664941","cross_references":{"pubmed":["34796674"],"doi":["10.1111/irv.12916"]}}