{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ban SP"],"funding":["Korea Health Industry Development Institute","Ministry of Health and Welfare"],"pagination":["765-771"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9666239"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["65(6)"],"pubmed_abstract":["<h4>Objective</h4>Stent-assisted coil embolization (SAC) has been increasingly used to treat various types of intracranial aneurysms. Delayed thromboembolic complications are major concerns regarding this procedure, so dual antiplatelet therapy with aspirin and clopidogrel is needed. However, clinicians vary the duration of dual antiplatelet therapy after SAC, and no randomized study has been performed. This study aims to compare the safety and efficacy of long-term (12 months) dual antiplatelet therapy and shortterm dual antiplatelet therapy (6 months) after SAC for patients with unruptured intracranial aneurysms (UIAs).<h4>Methods</h4>This is a prospective, randomized and multicenter trial to investigate the optimal duration of dual antiplatelet therapy after SAC in patients with UIAs. S"],"journal":["Journal of Korean Neurosurgical Society"],"pubmed_title":["Optimal Duration of Dual Antiplatelet Therapy after Stent- Assisted Coil Embolization of Unruptured Intracranial Aneurysms : A Prospective Randomized Multicenter Trial."],"pmcid":["PMC9666239"],"funding_grant_id":["HC20C0057"],"pubmed_authors":["Kwon OK","Kim CH","Park SQ","Kwon HJ","Kim KM","Ban SP","Kim YD","Chung J","Lim YC","Park KY","Kim BT","Byoun HS","Oh JS","Choi JH","Kim YW","Park JC"],"additional_accession":[]},"is_claimable":false,"name":"Optimal Duration of Dual Antiplatelet Therapy after Stent- Assisted Coil Embolization of Unruptured Intracranial Aneurysms : A Prospective Randomized Multicenter Trial.","description":"<h4>Objective</h4>Stent-assisted coil embolization (SAC) has been increasingly used to treat various types of intracranial aneurysms. Delayed thromboembolic complications are major concerns regarding this procedure, so dual antiplatelet therapy with aspirin and clopidogrel is needed. However, clinicians vary the duration of dual antiplatelet therapy after SAC, and no randomized study has been performed. This study aims to compare the safety and efficacy of long-term (12 months) dual antiplatelet therapy and shortterm dual antiplatelet therapy (6 months) after SAC for patients with unruptured intracranial aneurysms (UIAs).<h4>Methods</h4>This is a prospective, randomized and multicenter trial to investigate the optimal duration of dual antiplatelet therapy after SAC in patients with UIAs. S","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-19T22:49:54.556Z","creation":"2025-04-19T22:49:54.556Z"},"accession":"S-EPMC9666239","cross_references":{"pubmed":["35707971"],"doi":["10.3340/jkns.2022.0082"]}}