{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liu Y"],"funding":["NIBIB NIH HHS","Cancer Prevention and Research Institute of Texas","National Institute of Biomedical Imaging and Bioengineering"],"pagination":["8970-8980"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9670236"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(43)"],"pubmed_abstract":["Liposomes have been widely used in both medical imaging and drug delivery fields due to their excellent biocompatibility and easy surface modification. Recently our lab reported for the first-time the implementation of temperature-sensitive and indocyanine green (ICG)-encapsulated liposome microparticles for <i>in vivo</i> ultrasound-switchable fluorescence (USF) imaging. A previous study showed that liposome microparticles achieved USF imaging in centimeter-deep tissue. This study aimed to control the size of liposomes at the nanoscale and study the size effect on the USF imaging depth. Also, we explored the feasibility of combining USF imaging with ultrasound-controlled release. Liposomes were synthesized <i>via</i> the hydration method and the size was controlled by an extruding process"],"journal":["Journal of materials chemistry. B"],"pubmed_title":["Size effect of liposomes on centimeter-deep ultrasound-switchable fluorescence imaging and ultrasound-controlled release."],"pmcid":["PMC9670236"],"funding_grant_id":["R15 EB030809","RP170564","1R15EB030809-01"],"pubmed_authors":["Liu Y","Ren L","Yuan B","Yao T"],"additional_accession":[]},"is_claimable":false,"name":"Size effect of liposomes on centimeter-deep ultrasound-switchable fluorescence imaging and ultrasound-controlled release.","description":"Liposomes have been widely used in both medical imaging and drug delivery fields due to their excellent biocompatibility and easy surface modification. Recently our lab reported for the first-time the implementation of temperature-sensitive and indocyanine green (ICG)-encapsulated liposome microparticles for <i>in vivo</i> ultrasound-switchable fluorescence (USF) imaging. A previous study showed that liposome microparticles achieved USF imaging in centimeter-deep tissue. This study aimed to control the size of liposomes at the nanoscale and study the size effect on the USF imaging depth. Also, we explored the feasibility of combining USF imaging with ultrasound-controlled release. Liposomes were synthesized <i>via</i> the hydration method and the size was controlled by an extruding process","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-04T07:45:13.246Z","creation":"2025-04-04T07:45:13.246Z"},"accession":"S-EPMC9670236","cross_references":{"pubmed":["36285768"],"doi":["10.1039/d2tb01343f"]}}