{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["38"],"submitter":["Schneider S"],"pubmed_abstract":["<h4>Background and purpose</h4>Motion mitigation is of crucial importance in particle therapy (PT) of patients with abdominal tumors to ensure high-precision irradiation. Magnetic resonance imaging (MRI) is an excellent modality for target volume delineation and motion estimation of mobile soft-tissue tumors. Thus, the aims of this study were to develop an MRI- and PT-compatible abdominal compression device, to investigate its effect on pancreas motion reduction, and to evaluate patient tolerability and acceptance.<h4>Materials and methods</h4>In a prospective clinical study, 16 patients with abdominal tumors received an individualized polyethylene-based abdominal corset. Pancreas motion was analyzed using time- and phase resolved MRI scans (orthogonal 2D-cine and 4D MRI) with and without "],"journal":["Clinical and translational radiation oncology"],"pagination":["111-116"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9672128"],"repository":["biostudies-literature"],"pubmed_title":["Reduction of intrafraction pancreas motion using an abdominal corset compatible with proton therapy and MRI."],"pmcid":["PMC9672128"],"pubmed_authors":["Lohaus F","Schneider S","Hoffmann AL","Valentini C","Haak D","Thiele J","Jentsch C","Platzek I","G C Troost E","Stefanowicz S"],"additional_accession":[]},"is_claimable":false,"name":"Reduction of intrafraction pancreas motion using an abdominal corset compatible with proton therapy and MRI.","description":"<h4>Background and purpose</h4>Motion mitigation is of crucial importance in particle therapy (PT) of patients with abdominal tumors to ensure high-precision irradiation. Magnetic resonance imaging (MRI) is an excellent modality for target volume delineation and motion estimation of mobile soft-tissue tumors. Thus, the aims of this study were to develop an MRI- and PT-compatible abdominal compression device, to investigate its effect on pancreas motion reduction, and to evaluate patient tolerability and acceptance.<h4>Materials and methods</h4>In a prospective clinical study, 16 patients with abdominal tumors received an individualized polyethylene-based abdominal corset. Pancreas motion was analyzed using time- and phase resolved MRI scans (orthogonal 2D-cine and 4D MRI) with and without ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-19T16:13:03.09Z","creation":"2025-04-19T16:13:03.09Z"},"accession":"S-EPMC9672128","cross_references":{"pubmed":["36407488"],"doi":["10.1016/j.ctro.2022.11.006"]}}