{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["22(1)"],"submitter":["Sinn K"],"pubmed_abstract":["<h4>Purpose</h4>The prognostic value of pretreatment and preoperative fibrinogen plasma levels and the modified Glasgow prognostic score (mGPS) in stage III/N2 non-small cell lung cancer (NSCLC) patients who receive neoadjuvant treatment followed by radical surgery is yet unclear.<h4>Methods</h4>Fibrinogen levels and mGPS of 84 patients with initial stage III/N2 NSCLC, who received neoadjuvant therapy followed by complete surgical resection from 2002 to 2014 were retrospectively analyzed and correlated with clinical parameters and overall survival (OS). Data were analyzed using log-rank and Cox regression analysis adjusted for clinical and pathological factors.<h4>Results</h4>Median serum fibrinogen level after neoadjuvant treatment was 439 mg/dL (IQR 158 mg/dL). Elevated fibrinogen levels"],"journal":["BMC cancer"],"pagination":["1197"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9675967"],"repository":["biostudies-literature"],"pubmed_title":["Impact of fibrinogen levels and modified Glasgow prognostic score on survival of stage III/N2 non-small cell lung cancer patients treated with neoadjuvant therapy and radical resection."],"pmcid":["PMC9675967"],"pubmed_authors":["Klepetko W","Grusch M","Hoda MA","Hoetzenecker K","Klikovits T","Sinn K","Mosleh B","Gompelmann D"],"additional_accession":[]},"is_claimable":false,"name":"Impact of fibrinogen levels and modified Glasgow prognostic score on survival of stage III/N2 non-small cell lung cancer patients treated with neoadjuvant therapy and radical resection.","description":"<h4>Purpose</h4>The prognostic value of pretreatment and preoperative fibrinogen plasma levels and the modified Glasgow prognostic score (mGPS) in stage III/N2 non-small cell lung cancer (NSCLC) patients who receive neoadjuvant treatment followed by radical surgery is yet unclear.<h4>Methods</h4>Fibrinogen levels and mGPS of 84 patients with initial stage III/N2 NSCLC, who received neoadjuvant therapy followed by complete surgical resection from 2002 to 2014 were retrospectively analyzed and correlated with clinical parameters and overall survival (OS). Data were analyzed using log-rank and Cox regression analysis adjusted for clinical and pathological factors.<h4>Results</h4>Median serum fibrinogen level after neoadjuvant treatment was 439 mg/dL (IQR 158 mg/dL). Elevated fibrinogen levels","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-18T22:30:07.556Z","creation":"2025-04-07T10:14:39.981Z"},"accession":"S-EPMC9675967","cross_references":{"pubmed":["36403011"],"doi":["10.1186/s12885-022-10298-9"]}}