{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cheng Y"],"funding":["the Belt & Road Program","the Science and Technology Planning Projects of Fuzhou","the Natural Science Foundation of Fujian Province","the Young and Middle-aged Teacher Education Research Project of Fujian Province","the Ministry of Science and Technology of China","the Science and Technology Planning Projects of Fuzhou Institute of Oceanography","the National Natural Science Foundation of China"],"pagination":["943-956"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9676092"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(11)"],"pubmed_abstract":["Objectives
Primary tumor treatment through surgical resection and adjuvant therapy has been extensively studied, but there is a lack of effective strategies and drugs for the treatment of tumor metastases. Here, we describe a functional product based on a combination of compounds, which can be used as an adjuvant therapy and has well-known mechanisms for inhibiting cancer metastases, improving anti-cancer treatment, and enhancing immunity and antioxidant capacity. Our designed combination, named MVBL, consists of four inexpensive compounds: L-selenium-methylselenocysteine (MSC), D-α-tocopheryl succinic acid (VES), β-carotene (β-Ca), and L-lysine (Lys).Methods
The effects of MVBL on cell viability, cell cycle, cell apoptosis, cell migration, cell invasion, reactive oxyge"],"journal":["Journal of Zhejiang University. Science. B"],"pubmed_title":["Combination of Se-methylselenocysteine, D-α-tocopheryl succinate, β-carotene, and L-lysine can prevent cancer metastases using as an adjuvant therapy."],"pmcid":["PMC9676092"],"funding_grant_id":["KXPT-2021-3","2021S094","2015CB931804","81961138017 and 81703555","2021F08","2021J011046 and 2020J01859","JAT200412"],"pubmed_authors":["Zhai S","Li S","Lu Y","Lian S","Wang J","Jia L","Cheng Y","Deng X"],"additional_accession":[]},"is_claimable":false,"name":"Combination of Se-methylselenocysteine, D-α-tocopheryl succinate, β-carotene, and L-lysine can prevent cancer metastases using as an adjuvant therapy.","description":"Objectives
Primary tumor treatment through surgical resection and adjuvant therapy has been extensively studied, but there is a lack of effective strategies and drugs for the treatment of tumor metastases. Here, we describe a functional product based on a combination of compounds, which can be used as an adjuvant therapy and has well-known mechanisms for inhibiting cancer metastases, improving anti-cancer treatment, and enhancing immunity and antioxidant capacity. Our designed combination, named MVBL, consists of four inexpensive compounds: L-selenium-methylselenocysteine (MSC), D-α-tocopheryl succinic acid (VES), β-carotene (β-Ca), and L-lysine (Lys).Methods
The effects of MVBL on cell viability, cell cycle, cell apoptosis, cell migration, cell invasion, reactive oxyge","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-21T21:28:31.665Z","creation":"2025-04-05T18:21:48.541Z"},"accession":"S-EPMC9676092","cross_references":{"pubmed":["36379613"],"doi":["10.1631/jzus.b2200232","10.1631/jzus.B2200232"]}}