biostudies-literatureUnknown24Woodfield J<h4>Background</h4>Cauda equina syndrome (CES) results from nerve root compression in the lumbosacral spine, usually due to a prolapsed intervertebral disc. Evidence for management of CES is limited by its infrequent occurrence and lack of standardised clinical definitions and outcome measures.<h4>Methods</h4>This is a prospective multi-centre observational cohort study of adults with CES in the UK. We assessed presentation, investigation, management, and all Core Outcome Set domains up to one year post-operatively using clinician and participant reporting. Univariable and multivariable associations with the Oswestry Disability Index (ODI) and urinary outcomes were investigated.<h4>Findings</h4>In 621 participants with CES, catheterisation for urinary retention was required pre-operativelyThe Lancet regional health. Europe100545https://www.ebi.ac.uk/biostudies/studies/S-EPMC9678980biostudies-literaturePresentation, management, and outcomes of cauda equina syndrome up to one year after surgery, using clinician and participant reporting: A multi-centre prospective cohort study.PMC9678980Copley PCStatham PFChiverton NAhmed UWhitcher AHaliasos NDurst AZGill JRGordon RCunningham YHughes LPatel NBritish Neurosurgical Trainee Research CollaborativeJohn BPoon MTCStatham PFXAmarouche MElson BStokes SMohmoud KAKumaria AIbrahim RMorrison RBateman AKennion OSrikandarajah NClark SAl-Mahfoudh RDavies BThanabalasundaram GBhatti ILammy SDeore SSell PJLea MSheikh AUCES CollaboratorsAbdelsadg MStrachan ERasul FTBodkin PRoy HDurnford AEdlmann ESadek ARWhite DManfield JGhosh AHoeritzauer IHabeebullah APoon MTDuncan JJung JMishra PAjmi QBonanos GGardner AShafafy RDerham CBaig Mirza APhilip ADemetriades AKPrasad KSMEdwards-Bailey AKlejnotowska ARajwani KLaCava RGrenfell RSivasubramaniam VBoukas ASpink GPandit AThorpe PPronin SArora MGlasmacher SAHussain SAbulaila MMZolnourian AHolmes DUlbricht CBommireddy LHussain MHammett THill CSBusby CMurray OElserius ABrennan RAndalib ABurton OMoon RFountain DMSchramm MSharma HDardis RMerola JSofela AScicluna GNnandi CPujara SPurushothaman BMannion RNader-Sepahi AJamjoom AABMoon RDCDherijha MMacCormac OEames NThakar CJamjoom AAAwan MDyson EWDarwish SCudlip SJoshi SLawrence ALiew ILeung AHDobson GAli CFadelalla MBennett IBourne JGrahovac GWoodfield JBorg AKhan MWilby MBrown KWatts ABrown JHossain-Ibrahim KLuo WWhitehouse KHannan CJfalsePresentation, management, and outcomes of cauda equina syndrome up to one year after surgery, using clinician and participant reporting: A multi-centre prospective cohort study.<h4>Background</h4>Cauda equina syndrome (CES) results from nerve root compression in the lumbosacral spine, usually due to a prolapsed intervertebral disc. Evidence for management of CES is limited by its infrequent occurrence and lack of standardised clinical definitions and outcome measures.<h4>Methods</h4>This is a prospective multi-centre observational cohort study of adults with CES in the UK. We assessed presentation, investigation, management, and all Core Outcome Set domains up to one year post-operatively using clinician and participant reporting. Univariable and multivariable associations with the Oswestry Disability Index (ODI) and urinary outcomes were investigated.<h4>Findings</h4>In 621 participants with CES, catheterisation for urinary retention was required pre-operatively2023-01-01T00:00:00Z2023 Jan2025-04-18T14:59:05.065Z2025-04-07T01:24:21.826ZS-EPMC96789803642637810.1016/j.lanepe.2022.100545