biostudies-literatureUnknown10Yang X<h4>Purpose</h4>We performed this study to evaluate the association of socioeconomic status (SES) factors with cancer-specific survival (CSS) of patients with non-small cell lung cancer (NSCLC). We further assessed the predictive value of a novel Tumor Node Metastasis (TNM)-SES staging system, combining the TNM stage with the SES stage.<h4>Methods</h4>Using the Surveillance, Epidemiology, and End Results (SEER) database, we selected 40,378 patients diagnosed with NSCLC from 2012 to 2016. Cox regression method and Harrell's concordance index (C-index) were performed to select the SES factors related to CSS and evaluate the predictive ability of the novel TNM-SES stage. We used Kaplan-Meier curves and a log-rank test to conduct a survival analysis.<h4>Results</h4>We identified four SES factoFrontiers in public health992944https://www.ebi.ac.uk/biostudies/studies/S-EPMC9679653biostudies-literatureImpact of socioeconomic status on cancer staging, survival in non-small cell lung cancer.PMC9679653Yang XDeng LWang GZhou YLi MfalseImpact of socioeconomic status on cancer staging, survival in non-small cell lung cancer.<h4>Purpose</h4>We performed this study to evaluate the association of socioeconomic status (SES) factors with cancer-specific survival (CSS) of patients with non-small cell lung cancer (NSCLC). We further assessed the predictive value of a novel Tumor Node Metastasis (TNM)-SES staging system, combining the TNM stage with the SES stage.<h4>Methods</h4>Using the Surveillance, Epidemiology, and End Results (SEER) database, we selected 40,378 patients diagnosed with NSCLC from 2012 to 2016. Cox regression method and Harrell's concordance index (C-index) were performed to select the SES factors related to CSS and evaluate the predictive ability of the novel TNM-SES stage. We used Kaplan-Meier curves and a log-rank test to conduct a survival analysis.<h4>Results</h4>We identified four SES facto2022-01-01T00:00:00Z20222025-04-25T21:02:16.066Z2025-04-06T08:34:21.292ZS-EPMC96796533642496010.3389/fpubh.2022.992944