biostudies-literatureJiang HKey project of Science and Technology Department of Liaoning Provincee063082https://www.ebi.ac.uk/biostudies/studies/S-EPMC9680142biostudies-literatureUnknown12(11)<h4>Objective</h4>To develop and evaluate a psychosocial adaptation (PSA) questionnaire of women with breast cancer treated with adjuvant endocrine therapy (AET).<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Conducted study in a tertiary care centre in China from March to June 2021.<h4>Participants</h4>Women with breast cancer who have received AET.<h4>Methods</h4>Item development and extraction were based on literature, qualitative interviews (n=16) and assessment of content validity. 300 participants were recruited to perform item analysis, internal consistency reliability and exploratory factor analysis by cross-sectional studies. Finally, test-retest, criterion validity and confirmatory factor analysis of the questionnaire were performed with 96 respondents.<h4>Results</h4>An initial questionnaire was devised. The exploratory factor analysis demonstrated four factors: emotional response (six items), self-worth (five items), physical impacts (three items) and social communication (two items). The cumulative contribution of the factors was 65.057%. Cronbach's alpha coefficient of the questionnaire was 0.876. The correlation coefficient between the questionnaire and General Self-Efficacy Scale was 0.565 (p<0.01). A 16-item questionnaire and its factorial structure were confirmed.<h4>Conclusions</h4>The 16-item questionnaire had good reliability and validity. This could be a useful tool to assess the PSA levels among women with breast cancer treated with AET and provide a basis for further research.BMJ openDevelopment and evaluation of a psychosocial adaptation questionnaire for women with breast cancer treated with adjuvant endocrine therapy: a single-centre, cross-sectional study in China.PMC96801422008225010-3Jin FDong YJiang HZhang XXu HfalseDevelopment and evaluation of a psychosocial adaptation questionnaire for women with breast cancer treated with adjuvant endocrine therapy: a single-centre, cross-sectional study in China.<h4>Objective</h4>To develop and evaluate a psychosocial adaptation (PSA) questionnaire of women with breast cancer treated with adjuvant endocrine therapy (AET).<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Conducted study in a tertiary care centre in China from March to June 2021.<h4>Participants</h4>Women with breast cancer who have received AET.<h4>Methods</h4>Item development and extraction were based on literature, qualitative interviews (n=16) and assessment of content validity. 300 participants were recruited to perform item analysis, internal consistency reliability and exploratory factor analysis by cross-sectional studies. Finally, test-retest, criterion validity and confirmatory factor analysis of the questionnaire were performed with 96 respondents.<h4>Results</h4>An initial questionnaire was devised. The exploratory factor analysis demonstrated four factors: emotional response (six items), self-worth (five items), physical impacts (three items) and social communication (two items). The cumulative contribution of the factors was 65.057%. Cronbach's alpha coefficient of the questionnaire was 0.876. The correlation coefficient between the questionnaire and General Self-Efficacy Scale was 0.565 (p<0.01). A 16-item questionnaire and its factorial structure were confirmed.<h4>Conclusions</h4>The 16-item questionnaire had good reliability and validity. This could be a useful tool to assess the PSA levels among women with breast cancer treated with AET and provide a basis for further research.2022-01-01T00:00:00Z2022 Nov2025-06-01T02:48:33.903Z2025-06-01T02:48:33.903ZS-EPMC96801423641079810.1136/bmjopen-2022-063082