biostudies-literatureCohn AMCenter for Tobacco ProductsNIDA NIH HHSNIAID NIH HHSNational Institute on Drug Abusee067694https://www.ebi.ac.uk/biostudies/studies/S-EPMC9680144biostudies-literatureUnknown12(11)<h4>Introduction</h4>The Food and Drug Administration (FDA) announced its intention to reduce the nicotine content in cigarettes as a strategy to promote cessation and reduce smoking-related harm. A low nicotine product standard will apply to all cigarettes on the market, including menthol cigarettes. In December 2021, the FDA approved a modified risk tobacco product application for menthol and non-menthol flavoured very low nicotine cigarettes (VLNC) from the 22nd Century Group. Notably, experimentation with menthol cigarettes is linked to smoking progression, as well as greater nicotine dependence relative to non-menthol cigarette use. If menthol VLNCs are perceived as more appealing than non-menthol VLNCs, this would indicate that some aspect of menthol may maintain smoking even in the BMJ openImpact of a reduced nicotine standard on young adult appeal for menthol and non-menthol cigarettes.PMC9680144R01 AI050900R01DA050990-01R01 DA050990R01DA050990-02S1Donny EEhlke SJSmith MDenlinger-Apte RWyatt RCohen-Davidyan TVillanti ACDunn DCassidy RHatsukami DCohn AMNiznik TfalseImpact of a reduced nicotine standard on young adult appeal for menthol and non-menthol cigarettes.<h4>Introduction</h4>The Food and Drug Administration (FDA) announced its intention to reduce the nicotine content in cigarettes as a strategy to promote cessation and reduce smoking-related harm. A low nicotine product standard will apply to all cigarettes on the market, including menthol cigarettes. In December 2021, the FDA approved a modified risk tobacco product application for menthol and non-menthol flavoured very low nicotine cigarettes (VLNC) from the 22nd Century Group. Notably, experimentation with menthol cigarettes is linked to smoking progression, as well as greater nicotine dependence relative to non-menthol cigarette use. If menthol VLNCs are perceived as more appealing than non-menthol VLNCs, this would indicate that some aspect of menthol may maintain smoking even in the 2022-01-01T00:00:00Z2022 Nov2026-05-27T23:30:52.708Z2025-04-03T23:17:09.42ZS-EPMC96801443641080510.1136/bmjopen-2022-067694