biostudies-literatureUnknown23(11)Robar JL<h4>Purpose</h4>Thermoplastic immobilizers are used routinely in radiation therapy to achieve positioning accuracy. These devices are variable in quality as they are dependent on the skill of the human fabricator. We examine the potential multi jet fusion (MJF) 3D printing for the production immobilizers with a focus on the surface dosimetry of several MJF-printed PA12-based material candidates. Materials are compared with the goal of minimizing surface dose with comparison to standard thermoplastic. We introduce a novel metamaterial design for the shell of the immobilizer, with the aims of mechanical robustness and low-dose buildup. We demonstrate first examples of adult and pediatric cranial and head-and-neck immobilizers.<h4>Methods</h4>Three different PA12 materials were examined and cJournal of applied clinical medical physicse13773https://www.ebi.ac.uk/biostudies/studies/S-EPMC9680581biostudies-literatureNovel multi jet fusion 3D-printed patient immobilization for radiation therapy.PMC9680581Young CCheng XStasiak JHulick KOrbovic RVerzwyvelt VShepherd MFedullo SRobar JLKaiser PKammerzell BDiMarco SMajcher CfalseNovel multi jet fusion 3D-printed patient immobilization for radiation therapy.<h4>Purpose</h4>Thermoplastic immobilizers are used routinely in radiation therapy to achieve positioning accuracy. These devices are variable in quality as they are dependent on the skill of the human fabricator. We examine the potential multi jet fusion (MJF) 3D printing for the production immobilizers with a focus on the surface dosimetry of several MJF-printed PA12-based material candidates. Materials are compared with the goal of minimizing surface dose with comparison to standard thermoplastic. We introduce a novel metamaterial design for the shell of the immobilizer, with the aims of mechanical robustness and low-dose buildup. We demonstrate first examples of adult and pediatric cranial and head-and-neck immobilizers.<h4>Methods</h4>Three different PA12 materials were examined and c2022-01-01T00:00:00Z2022 Nov2025-04-18T14:59:51.597Z2025-04-07T01:24:56.312ZS-EPMC96805813605299010.1002/acm2.13773