{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ochs-Balcom HM"],"funding":["NHLBI NIH HHS","NCI NIH HHS","U.S. Department of Health &amp; Human Services | National Institutes of Health"],"pagination":["1983-1990"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9681872"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["127(11)"],"pubmed_abstract":["<h4>Background</h4>Obesity disproportionately affects African American (AA) women and has been shown to increase ovarian cancer risk, with some suggestions that the association may differ by race.<h4>Methods</h4>We evaluated body mass index (BMI) and invasive epithelial ovarian cancer (EOC) risk in a pooled study of case-control and nested case-control studies including AA and White women. We evaluated both young adult and recent BMI (within the last 5 years). Associations were estimated using multi-level and multinomial logistic regression models.<h4>Results</h4>The sample included 1078 AA cases, 2582 AA controls, 3240 White cases and 9851 White controls. We observed a higher risk for the non-high-grade serous (NHGS) histotypes for AA women with obesity (OR<sub>BMI 30+</sub>= 1.62, 95% CI"],"journal":["British journal of cancer"],"pubmed_title":["Racial differences in the association of body mass index and ovarian cancer risk in the OCWAA Consortium."],"pmcid":["PMC9681872"],"funding_grant_id":["R01 CA076016","U01 CA164974","R01-CA142081","R01 CA207260","R01-CA058420","UM1 CA173642","P30 CA014089","R01-CA076016","UM1-CA164974","HHSN268201600002C","UM1 CA164974","HHSN268201600003C","R01-CA207260","K01 CA212056","U01-CA164974","R01 CA058598","HHSN268201600001C","R01 CA058420","R01-CA17054","HHSN268201600018C","HHSN268201600004C","K01-CA212056","R01-CA58598","R01 CA142081"],"pubmed_authors":["Myers E","Schildkraut JM","Ochs-Balcom HM","Joslin CE","Bethea TN","Dempsey LF","Rosenow W","Bandera EV","Camacho F","Peres LC","Guertin KA","Beeghly-Fadiel A","Wu AH","Moorman PG","Wendy Setiawan V","Rosenberg L","Johnson C","Harris HR","Qin B"],"additional_accession":[]},"is_claimable":false,"name":"Racial differences in the association of body mass index and ovarian cancer risk in the OCWAA Consortium.","description":"<h4>Background</h4>Obesity disproportionately affects African American (AA) women and has been shown to increase ovarian cancer risk, with some suggestions that the association may differ by race.<h4>Methods</h4>We evaluated body mass index (BMI) and invasive epithelial ovarian cancer (EOC) risk in a pooled study of case-control and nested case-control studies including AA and White women. We evaluated both young adult and recent BMI (within the last 5 years). Associations were estimated using multi-level and multinomial logistic regression models.<h4>Results</h4>The sample included 1078 AA cases, 2582 AA controls, 3240 White cases and 9851 White controls. We observed a higher risk for the non-high-grade serous (NHGS) histotypes for AA women with obesity (OR<sub>BMI 30+</sub>= 1.62, 95% CI","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2026-07-14T15:35:08.631Z","creation":"2025-04-20T03:27:52.954Z"},"accession":"S-EPMC9681872","cross_references":{"pubmed":["36138071"],"doi":["10.1038/s41416-022-01981-6"]}}