biostudies-literatureUnknown2022Nasiruddin<i>Millettia speciosa</i> is a plant extensively used as an important component in Chinese herbal medicine and food-based medicines. The present study was carried out to determine the total flavonoid content (TFC), volatile phytoconstituents, and pharmacological activities, i.e., antityrosinase, sunscreen, and anticancer activity, of different fractions of <i>M. speciosa</i> stem. Different organic solvents of increasing polarity, i.e., petroleum ether (PE), ethyl acetate (EtOAc), and methanol (MeOH), were used for extraction. The highest total flavonoid content, i.e., 48.30 ± 0.90%, was reported for PE extract. Various important phytocomponents were revealed by gas chromatography-mass spectroscopy (GC-MS) analysis. Based on abundance, the major compounds were n-hexadecanoic acid (16.654%)BioMed research international2486979https://www.ebi.ac.uk/biostudies/studies/S-EPMC9683946biostudies-literatureComparison of Phytochemical Constituents and Pharmacological Activities of Various Solvent Extracts Obtained from <i>Millettia speciosa</i> Stem Powder.PMC9683946Minghui JLi XSafir WZeeshan MChen GKhan AZeb SNuman MNasiruddinMasood TKhan MAfalseComparison of Phytochemical Constituents and Pharmacological Activities of Various Solvent Extracts Obtained from <i>Millettia speciosa</i> Stem Powder.<i>Millettia speciosa</i> is a plant extensively used as an important component in Chinese herbal medicine and food-based medicines. The present study was carried out to determine the total flavonoid content (TFC), volatile phytoconstituents, and pharmacological activities, i.e., antityrosinase, sunscreen, and anticancer activity, of different fractions of <i>M. speciosa</i> stem. Different organic solvents of increasing polarity, i.e., petroleum ether (PE), ethyl acetate (EtOAc), and methanol (MeOH), were used for extraction. The highest total flavonoid content, i.e., 48.30 ± 0.90%, was reported for PE extract. Various important phytocomponents were revealed by gas chromatography-mass spectroscopy (GC-MS) analysis. Based on abundance, the major compounds were n-hexadecanoic acid (16.654%)2022-01-01T00:00:00Z20222025-04-04T19:51:30.133Z2025-04-04T19:51:30.133ZS-EPMC96839463644035410.1155/2022/2486979