{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Peetermans M"],"funding":["Fonds Wetenschappelijk Onderzoek"],"pagination":["37-49"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9684759"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["49(1)"],"pubmed_abstract":["<h4>Purpose</h4>The impact of body mass index (BMI) on outcomes in respiratory failure necessitating extracorporeal membrane oxygenation (ECMO) has been poorly described. We aimed to assess: (i) whether adults with class II obesity or more (BMI ≥ 35 kg/m<sup>2</sup>) have worse outcomes than lean counterparts, (ii) the form of the relationship between BMI and outcomes, (iii) whether a cutoff marking futility can be identified.<h4>Methods</h4>A retrospective analysis of the Extracorporeal Life Support Organization (ELSO) Registry from 1/1/2010 to 31/12/2020 was conducted. Impact of BMI ≥ 35 kg/m<sup>2</sup> was assessed with propensity-score (PS) matching, inverse propensity-score weighted (IPSW) and multivariable models (MV), adjusting for a priori identified confounders. Primary outcome w"],"journal":["Intensive care medicine"],"pubmed_title":["Impact of BMI on outcomes in respiratory ECMO: an ELSO registry study."],"pmcid":["PMC9684759"],"funding_grant_id":["1805121N"],"pubmed_authors":["Hermans G","Vlaar APJ","Wauters J","Peetermans M","Guler I","Combes A","Meersseman P","Wilmer A","Meyns B"],"additional_accession":[]},"is_claimable":false,"name":"Impact of BMI on outcomes in respiratory ECMO: an ELSO registry study.","description":"<h4>Purpose</h4>The impact of body mass index (BMI) on outcomes in respiratory failure necessitating extracorporeal membrane oxygenation (ECMO) has been poorly described. We aimed to assess: (i) whether adults with class II obesity or more (BMI ≥ 35 kg/m<sup>2</sup>) have worse outcomes than lean counterparts, (ii) the form of the relationship between BMI and outcomes, (iii) whether a cutoff marking futility can be identified.<h4>Methods</h4>A retrospective analysis of the Extracorporeal Life Support Organization (ELSO) Registry from 1/1/2010 to 31/12/2020 was conducted. Impact of BMI ≥ 35 kg/m<sup>2</sup> was assessed with propensity-score (PS) matching, inverse propensity-score weighted (IPSW) and multivariable models (MV), adjusting for a priori identified confounders. Primary outcome w","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-25T19:58:54.007Z","creation":"2025-02-19T01:55:38.383Z"},"accession":"S-EPMC9684759","cross_references":{"pubmed":["36416896"],"doi":["10.1007/s00134-022-06926-4"]}}